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A PTER-dependent pathway of taurine metabolism linked to energy balance.
Wei W, Lyu X, Markhard AL, Fu S, Mardjuki RE, Cavanagh PE, Zeng X, Rajniak J, Lu N, Xiao S, Zhao M, Moya-Garzon MD, Truong SD, Chou JC, Wat LW, Chidambaranathan-Reghupaty S, Coassolo L, Xu D, Shen F, Huang W, Ramirez CB, Jang C, Svensson KJ, Fischbach MA, Long JZ. Wei W, et al. Among authors: long jz. bioRxiv [Preprint]. 2024 Mar 22:2024.03.21.586194. doi: 10.1101/2024.03.21.586194. bioRxiv. 2024. PMID: 38562797 Free PMC article. Preprint.
Lac-Phe mediates the anti-obesity effect of metformin.
Xiao S, Li VL, Lyu X, Chen X, Wei W, Abbasi F, Knowles JW, Deng S, Tiwari G, Shi X, Zheng S, Farrell L, Chen ZZ, Taylor KD, Guo X, Goodarzi MO, Wood AC, Ida Chen YD, Lange LA, Rich SS, Rotter JI, Clish CB, Tahir UA, Gerszten RE, Benson MD, Long JZ. Xiao S, et al. Among authors: long jz. bioRxiv [Preprint]. 2023 Nov 4:2023.11.02.565321. doi: 10.1101/2023.11.02.565321. bioRxiv. 2023. PMID: 37961394 Free PMC article. Preprint.
Organism-wide, cell-type-specific secretome mapping of exercise training in mice.
Wei W, Riley NM, Lyu X, Shen X, Guo J, Raun SH, Zhao M, Moya-Garzon MD, Basu H, Sheng-Hwa Tung A, Li VL, Huang W, Wiggenhorn AL, Svensson KJ, Snyder MP, Bertozzi CR, Long JZ. Wei W, et al. Among authors: long jz. Cell Metab. 2023 Jul 11;35(7):1261-1279.e11. doi: 10.1016/j.cmet.2023.04.011. Epub 2023 May 3. Cell Metab. 2023. PMID: 37141889
CYP4F2 is a human-specific determinant of circulating N-acyl amino acid levels.
Tanzo JT, Li VL, Wiggenhorn AL, Moya-Garzon MD, Wei W, Lyu X, Dong W, Tahir UA, Chen ZZ, Cruz DE, Deng S, Shi X, Zheng S, Guo Y, Sims M, Abu-Remaileh M, Wilson JG, Gerszten RE, Long JZ, Benson MD. Tanzo JT, et al. Among authors: long jz. J Biol Chem. 2023 Jun;299(6):104764. doi: 10.1016/j.jbc.2023.104764. Epub 2023 Apr 28. J Biol Chem. 2023. PMID: 37121548 Free PMC article.
A Cell Cycle-Dependent Ferroptosis Sensitivity Switch Governed by EMP2.
Rodencal J, Kim N, Li VL, He A, Lange M, He J, Tarangelo A, Schafer ZT, Olzmann JA, Sage J, Long JZ, Dixon SJ. Rodencal J, et al. Among authors: long jz. bioRxiv [Preprint]. 2023 Jul 19:2023.07.19.549715. doi: 10.1101/2023.07.19.549715. bioRxiv. 2023. PMID: 37502927 Free PMC article. Preprint.
SLC17 transporters mediate renal excretion of Lac-Phe in mice and humans.
Li VL, Xiao S, Schlosser P, Scherer N, Wiggenhorn AL, Spaas J, Tung AS, Karoly ED, Köttgen A, Long JZ. Li VL, et al. Among authors: long jz. bioRxiv [Preprint]. 2024 Apr 18:2024.04.18.589815. doi: 10.1101/2024.04.18.589815. bioRxiv. 2024. PMID: 38659895 Free PMC article. Preprint.
Lac-Phe mediates the effects of metformin on food intake and body weight.
Xiao S, Li VL, Lyu X, Chen X, Wei W, Abbasi F, Knowles JW, Tung AS, Deng S, Tiwari G, Shi X, Zheng S, Farrell L, Chen ZZ, Taylor KD, Guo X, Goodarzi MO, Wood AC, Chen YI, Lange LA, Rich SS, Rotter JI, Clish CB, Tahir UA, Gerszten RE, Benson MD, Long JZ. Xiao S, et al. Among authors: long jz. Nat Metab. 2024 Apr;6(4):659-669. doi: 10.1038/s42255-024-00999-9. Epub 2024 Mar 18. Nat Metab. 2024. PMID: 38499766
80 results