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Genome-wide analyses identify 21 infertility loci and over 400 reproductive hormone loci across the allele frequency spectrum.
Venkatesh SS, Wittemans LBL, Palmer DS, Baya NA, Ferreira T, Hill B, Lassen FH, Parker MJ, Reibe S, Elhakeem A, Banasik K, Bruun MT, Erikstrup C, Jensen BA, Juul A, Mikkelsen C, Nielsen HS, Ostrowski SR, Pedersen OB, Rohde PD, Sorensen E, Ullum H, Westergaard D, Haraldsson A, Holm H, Jonsdottir I, Olafsson I, Steingrimsdottir T, Steinthorsdottir V, Thorleifsson G, Figueredo J, Karjalainen MK, Pasanen A, Jacobs BM, Hubers N; Genes & Health Research Team; Estonian Biobank Research Team; Estonian Health Informatics Research Team; DBDS Genomic Consortium; FinnGen; Lippincott M, Fraser A, Lawlor DA, Timpson NJ, Nyegaard M, Stefansson K, Magi R, Laivuori H, van Heel DA, Boomsma DI, Balasubramanian R, Seminara SB, Chan YM, Laisk T, Lindgren CM. Venkatesh SS, et al. Among authors: elhakeem a. medRxiv [Preprint]. 2024 Mar 20:2024.03.19.24304530. doi: 10.1101/2024.03.19.24304530. medRxiv. 2024. PMID: 38562841 Free PMC article. Preprint.
The effect of maternal pre-/early-pregnancy BMI and pregnancy smoking and alcohol on congenital heart diseases: a parental negative control study.
Taylor K, Elhakeem A, Nader JLT, Yang T, Isaevska E, Richiardi L, Vrijkotte T, de Moira AP, Murray DM, Finn D, Mason D, Wright J, Oddie S, Roeleveld N, Harris JR, Nybo Andersen AM, Caputo M, Lawlor DA. Taylor K, et al. Among authors: elhakeem a. medRxiv [Preprint]. 2020 Nov 4:2020.09.29.20203786. doi: 10.1101/2020.09.29.20203786. medRxiv. 2020. PMID: 33173887 Free PMC article. Updated. Preprint.
Incorporating interactions into structured life course modelling approaches: A simulation study and applied example of the role of access to green space and socioeconomic position on cardiometabolic health.
Major-Smith D, Dvořák T, Elhakeem A, Lawlor DA, Tilling K, Smith ADAC. Major-Smith D, et al. Among authors: elhakeem a. medRxiv [Preprint]. 2023 Jan 25:2023.01.24.23284935. doi: 10.1101/2023.01.24.23284935. medRxiv. 2023. PMID: 36747796 Free PMC article. Preprint.
Genome-wide association study implicates novel loci and reveals candidate effector genes for longitudinal pediatric bone accrual.
Cousminer DL, Wagley Y, Pippin JA, Elhakeem A, Way GP, Pahl MC, McCormack SE, Chesi A, Mitchell JA, Kindler JM, Baird D, Hartley A, Howe L, Kalkwarf HJ, Lappe JM, Lu S, Leonard ME, Johnson ME, Hakonarson H, Gilsanz V, Shepherd JA, Oberfield SE, Greene CS, Kelly A, Lawlor DA, Voight BF, Wells AD, Zemel BS, Hankenson KD, Grant SFA. Cousminer DL, et al. Among authors: elhakeem a. Genome Biol. 2021 Jan 4;22(1):1. doi: 10.1186/s13059-020-02207-9. Genome Biol. 2021. PMID: 33397451 Free PMC article.
Effect of Maternal Prepregnancy/Early-Pregnancy Body Mass Index and Pregnancy Smoking and Alcohol on Congenital Heart Diseases: A Parental Negative Control Study.
Taylor K, Elhakeem A, Thorbjørnsrud Nader JL, Yang TC, Isaevska E, Richiardi L, Vrijkotte T, Pinot de Moira A, Murray DM, Finn D, Mason D, Wright J, Oddie S, Roeleveld N, Harris JR, Andersen AN, Caputo M, Lawlor DA. Taylor K, et al. Among authors: elhakeem a. J Am Heart Assoc. 2021 Jun;10(11):e020051. doi: 10.1161/JAHA.120.020051. Epub 2021 May 27. J Am Heart Assoc. 2021. PMID: 34039012 Free PMC article.
64 results