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Conserved long noncoding RNA TILAM promotes liver fibrosis through interaction with PML in HSCs.
Sun C, Zhou C, Daneshvar K, Ben Saad A, Kratkiewicz AJ, Toles BJ, Arghiani N, Hess A, Chen JY, Pondick JV, York SR, Li W, Moran SP, Gentile SD, Rahman RU, Li Z, Zhou P, Sparks RP, Habboub T, Kim BM, Choi MY, Affo S, Schwabe RF, Popov YV, Mullen AC. Sun C, et al. Among authors: affo s. Hepatology. 2024 Apr 2. doi: 10.1097/HEP.0000000000000822. Online ahead of print. Hepatology. 2024. PMID: 38563629
Fibroblasts in liver cancer: functions and therapeutic translation.
Affo S, Filliol A, Gores GJ, Schwabe RF. Affo S, et al. Lancet Gastroenterol Hepatol. 2023 Aug;8(8):748-759. doi: 10.1016/S2468-1253(23)00111-5. Epub 2023 Jun 26. Lancet Gastroenterol Hepatol. 2023. PMID: 37385282 Free article. Review.
Conserved long noncoding RNA TILAM promotes liver fibrosis through interaction with PML in hepatic stellate cells.
Sun C, Zhou C, Daneshvar K, Kratkiewicz AJ, Saad AB, Hess A, Chen JY, Pondick JV, York SR, Li W, Moran S, Gentile S, Rahman RU, Li Z, Sparks R, Habboub T, Kim BM, Choi MY, Affo S, Schwabe RF, Popov YV, Mullen AC. Sun C, et al. Among authors: affo s. bioRxiv [Preprint]. 2023 Jul 30:2023.07.29.551032. doi: 10.1101/2023.07.29.551032. bioRxiv. 2023. PMID: 37546982 Free PMC article. Updated. Preprint.
The purinergic P2Y14 receptor links hepatocyte death to hepatic stellate cell activation and fibrogenesis in the liver.
Mederacke I, Filliol A, Affo S, Nair A, Hernandez C, Sun Q, Hamberger F, Brundu F, Chen Y, Ravichandra A, Huebener P, Anke H, Shi H, Martínez García de la Torre RA, Smith JR, Henderson NC, Vondran FWR, Rothlin CV, Baehre H, Tabas I, Sancho-Bru P, Schwabe RF. Mederacke I, et al. Among authors: affo s. Sci Transl Med. 2022 Apr 6;14(639):eabe5795. doi: 10.1126/scitranslmed.abe5795. Epub 2022 Apr 6. Sci Transl Med. 2022. PMID: 35385339 Free PMC article.
CCL20 mediates lipopolysaccharide induced liver injury and is a potential driver of inflammation and fibrosis in alcoholic hepatitis.
Affò S, Morales-Ibanez O, Rodrigo-Torres D, Altamirano J, Blaya D, Dapito DH, Millán C, Coll M, Caviglia JM, Arroyo V, Caballería J, Schwabe RF, Ginès P, Bataller R, Sancho-Bru P. Affò S, et al. Gut. 2014 Nov;63(11):1782-92. doi: 10.1136/gutjnl-2013-306098. Epub 2014 Jan 10. Gut. 2014. PMID: 24415562 Free PMC article.
Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis.
Filliol A, Saito Y, Nair A, Dapito DH, Yu LX, Ravichandra A, Bhattacharjee S, Affo S, Fujiwara N, Su H, Sun Q, Savage TM, Wilson-Kanamori JR, Caviglia JM, Chin L, Chen D, Wang X, Caruso S, Kang JK, Amin AD, Wallace S, Dobie R, Yin D, Rodriguez-Fiallos OM, Yin C, Mehal A, Izar B, Friedman RA, Wells RG, Pajvani UB, Hoshida Y, Remotti HE, Arpaia N, Zucman-Rossi J, Karin M, Henderson NC, Tabas I, Schwabe RF. Filliol A, et al. Among authors: affo s. Nature. 2022 Oct;610(7931):356-365. doi: 10.1038/s41586-022-05289-6. Epub 2022 Oct 5. Nature. 2022. PMID: 36198802 Free PMC article.
37 results