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Reciprocal crosstalk between Th17 and mesothelial cells promotes metastasis-associated adhesion of ovarian cancer cells.
Neuhaus F, Lieber S, Shinkevich V, Steitz AM, Raifer H, Roth K, Finkernagel F, Worzfeld T, Burchert A, Keber C, Nist A, Stiewe T, Reinartz S, Beutgen VM, Graumann J, Pauck K, Garn H, Gaida M, Müller R, Huber M. Neuhaus F, et al. Among authors: worzfeld t. Clin Transl Med. 2024 Apr;14(4):e1604. doi: 10.1002/ctm2.1604. Clin Transl Med. 2024. PMID: 38566518 Free PMC article.
TRAIL-dependent apoptosis of peritoneal mesothelial cells by NK cells promotes ovarian cancer invasion.
Steitz AM, Schröder C, Knuth I, Keber CU, Sommerfeld L, Finkernagel F, Jansen JM, Wagner U, Müller-Brüsselbach S, Worzfeld T, Huber M, Beutgen VM, Graumann J, Pogge von Strandmann E, Müller R, Reinartz S. Steitz AM, et al. Among authors: worzfeld t. iScience. 2023 Nov 7;26(12):108401. doi: 10.1016/j.isci.2023.108401. eCollection 2023 Dec 15. iScience. 2023. PMID: 38047087 Free PMC article.
The SHDRA syndrome-associated gene TMEM260 encodes a protein-specific O-mannosyltransferase.
Larsen ISB, Povolo L, Zhou L, Tian W, Mygind KJ, Hintze J, Jiang C, Hartill V, Prescott K, Johnson CA, Mullegama SV, McConkie-Rosell A, McDonald M, Hansen L, Vakhrushev SY, Schjoldager KT, Clausen H, Worzfeld T, Joshi HJ, Halim A. Larsen ISB, et al. Among authors: worzfeld t. Proc Natl Acad Sci U S A. 2023 May 23;120(21):e2302584120. doi: 10.1073/pnas.2302584120. Epub 2023 May 15. Proc Natl Acad Sci U S A. 2023. PMID: 37186866 Free PMC article.
Plexin-B1 Mutation Drives Metastasis in Prostate Cancer Mouse Models.
Shorning B, Trent N, Griffiths DF, Worzfeld T, Offermanns S, Smalley MJ, Williamson M. Shorning B, et al. Among authors: worzfeld t. Cancer Res Commun. 2023 Mar 16;3(3):444-458. doi: 10.1158/2767-9764.CRC-22-0480. eCollection 2023 Mar. Cancer Res Commun. 2023. PMID: 36936664 Free PMC article.
A semaphorin-plexin-Rasal1 signaling pathway inhibits gastrin expression and protects against peptic ulcers.
Xu R, Höß C, Swiercz JM, Brandt DT, Lutz V, Petersen N, Li R, Zhao D, Oleksy A, Creigh-Pulatmen T, Trokter M, Fedorova M, Atzberger A, Strandby RB, Olsen AA, Achiam MP, Matthews D, Huber M, Gröne HJ, Offermanns S, Worzfeld T. Xu R, et al. Among authors: worzfeld t. Sci Transl Med. 2022 Jul 20;14(654):eabf1922. doi: 10.1126/scitranslmed.abf1922. Epub 2022 Jul 20. Sci Transl Med. 2022. PMID: 35857828
An antagonistic monoclonal anti-Plexin-B1 antibody exerts therapeutic effects in mouse models of postmenopausal osteoporosis and multiple sclerosis.
Vogler M, Oleksy A, Schulze S, Fedorova M, Kojonazarov B, Nijjar S, Patel S, Jossi S, Sawmynaden K, Henry M, Brown R, Matthews D, Offermanns S, Worzfeld T. Vogler M, et al. Among authors: worzfeld t. J Biol Chem. 2022 Sep;298(9):102265. doi: 10.1016/j.jbc.2022.102265. Epub 2022 Jul 15. J Biol Chem. 2022. PMID: 35850304 Free PMC article.
Mechanochemical control of epidermal stem cell divisions by B-plexins.
Jiang C, Javed A, Kaiser L, Nava MM, Xu R, Brandt DT, Zhao D, Mayer B, Fernández-Baldovinos J, Zhou L, Höß C, Sawmynaden K, Oleksy A, Matthews D, Weinstein LS, Hahn H, Gröne HJ, Graumann PL, Niessen CM, Offermanns S, Wickström SA, Worzfeld T. Jiang C, et al. Among authors: worzfeld t. Nat Commun. 2021 Feb 26;12(1):1308. doi: 10.1038/s41467-021-21513-9. Nat Commun. 2021. PMID: 33637728 Free PMC article.
TTL-Expression Modulates Epithelial Morphogenesis.
Müller M, Ringer K, Hub F, Kamm N, Worzfeld T, Jacob R. Müller M, et al. Among authors: worzfeld t. Front Cell Dev Biol. 2021 Feb 5;9:635723. doi: 10.3389/fcell.2021.635723. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33614664 Free PMC article.
40 results