Chen L - Search Results

1

A novel deep generative model for mRNA vaccine development: Designing 5' UTRs with N1-methyl-pseudouridine modification.

Tang X, Huo M, Chen Y, Huang H, Qin S, Luo J, Qin Z, Jiang X, Liu Y, Duan X, Wang R, Chen L, Li H, Fan N, He Z, He X, Shen B, Li SC, Song X. Tang X, et al. Among authors: chen l, chen y. Acta Pharm Sin B. 2024 Apr;14(4):1814-1826. doi: 10.1016/j.apsb.2023.11.003. Epub 2023 Nov 5. Acta Pharm Sin B. 2024. PMID: 38572113 Free PMC article.

2

Detecting TAD-like domains from RNA-associated interactions.

Zhang YW, Chen L, Li SC. Zhang YW, et al. Among authors: chen l. Nucleic Acids Res. 2022 Aug 26;50(15):e88. doi: 10.1093/nar/gkac422. Nucleic Acids Res. 2022. PMID: 35639502 Free PMC article.

3

Incorporating cell hierarchy to decipher the functional diversity of single cells.

Chen L, Li SC. Chen L, et al. Nucleic Acids Res. 2023 Jan 25;51(2):e9. doi: 10.1093/nar/gkac1044. Nucleic Acids Res. 2023. PMID: 36373664 Free PMC article.

4

DeepMF: deciphering the latent patterns in omics profiles with a deep learning method.

Chen L, Xu J, Li SC. Chen L, et al. BMC Bioinformatics. 2019 Dec 27;20(Suppl 23):648. doi: 10.1186/s12859-019-3291-6. BMC Bioinformatics. 2019. PMID: 31881818 Free PMC article.

5

Quantitative annotations of T-Cell repertoire specificity.

Luo J, Wang X, Zou Y, Chen L, Liu W, Zhang W, Li SC. Luo J, et al. Among authors: chen l. Brief Bioinform. 2023 May 19;24(3):bbad175. doi: 10.1093/bib/bbad175. Brief Bioinform. 2023. PMID: 37150761

6

Heterogeneity in lung cancers by single-cell DNA sequencing.

Zhang L, Chen L, Li SC, Wang M, Li C, Song T, Ni Y, Yang Y, Liu Z, Yao M, Shen B, Li W. Zhang L, et al. Among authors: chen l. Clin Transl Med. 2023 Sep;13(9):e1388. doi: 10.1002/ctm2.1388. Clin Transl Med. 2023. PMID: 37649132 Free PMC article. No abstract available.

7

SpecHap: a diploid phasing algorithm based on spectral graph theory.

Yu Y, Chen L, Miao X, Li SC. Yu Y, et al. Among authors: chen l. Nucleic Acids Res. 2021 Nov 8;49(19):e114. doi: 10.1093/nar/gkab709. Nucleic Acids Res. 2021. PMID: 34403470 Free PMC article.

8

SMURF: embedding single-cell RNA-seq data with matrix factorization preserving self-consistency.

Pu J, Wang B, Liu X, Chen L, Li SC. Pu J, et al. Among authors: chen l. Brief Bioinform. 2023 Mar 19;24(2):bbad026. doi: 10.1093/bib/bbad026. Brief Bioinform. 2023. PMID: 36715274

9

Corrigendum: Oviz-Bio: a web-based platform for interactive cancer genomics data visualization.

Jia W, Li H, Li S, Chen L, Li SC. Jia W, et al. Among authors: chen l. Nucleic Acids Res. 2020 Aug 20;48(14):8203-8204. doi: 10.1093/nar/gkaa553. Nucleic Acids Res. 2020. PMID: 32573697 Free PMC article. No abstract available.

10

Deciphering complex breakage-fusion-bridge genome rearrangements with Ambigram.

Li C, Chen L, Pan G, Zhang W, Li SC. Li C, et al. Among authors: chen l. Nat Commun. 2023 Sep 8;14(1):5528. doi: 10.1038/s41467-023-41259-w. Nat Commun. 2023. PMID: 37684230 Free PMC article.

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