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Early molecular events of autosomal-dominant Alzheimer's disease in marmosets with PSEN1 mutations.
Homanics GE, Park JE, Bailey L, Schaeffer DJ, Schaeffer L, He J, Li S, Zhang T, Haber A, Spruce C, Greenwood A, Murai T, Schultz L, Mongeau L, Ha SK, Oluoch J, Stein B, Choi SH, Huhe H, Thathiah A, Strick PL, Carter GW, Silva AC, Sukoff Rizzo SJ. Homanics GE, et al. Among authors: thathiah a. Alzheimers Dement. 2024 May;20(5):3455-3471. doi: 10.1002/alz.13806. Epub 2024 Apr 4. Alzheimers Dement. 2024. PMID: 38574388 Free PMC article.
Marmosets as model systems for the study of Alzheimer's disease and related dementias: substantiation of physiological Tau 3R and 4R isoform expression and phosphorylation.
Huhe H, Shapley SM, Duong D, Wu F, Ha SK, Choi SH, Kofler J, Mou Y, Guimaraes TR, Thathiah A, Schaeffer LKH, Carter GW, Seyfried NT, Silva AC, Sukoff Rizzo SJ. Huhe H, et al. Among authors: thathiah a. bioRxiv [Preprint]. 2024 Apr 29:2024.04.26.590453. doi: 10.1101/2024.04.26.590453. bioRxiv. 2024. PMID: 38746277 Free PMC article. Preprint.
Deletion of SERF2 in mice delays embryonic development and alters amyloid deposit structure in the brain.
Stroo E, Janssen L, Sin O, Hogewerf W, Koster M, Harkema L, Youssef SA, Beschorner N, Wolters AH, Bakker B, Becker L, Garrett L, Marschall S, Hoelter SM, Wurst W, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Thathiah A, Foijer F, van de Sluis B, van Deursen J, Jucker M, de Bruin A, Nollen EA. Stroo E, et al. Among authors: thathiah a. Life Sci Alliance. 2023 May 2;6(7):e202201730. doi: 10.26508/lsa.202201730. Print 2023 Jul. Life Sci Alliance. 2023. PMID: 37130781 Free PMC article.
G protein-biased GPR3 signaling ameliorates amyloid pathology in a preclinical Alzheimer's disease mouse model.
Huang Y, Rafael Guimarães T, Todd N, Ferguson C, Weiss KM, Stauffer FR, McDermott B, Hurtle BT, Saito T, Saido TC, MacDonald ML, Homanics GE, Thathiah A. Huang Y, et al. Among authors: thathiah a. Proc Natl Acad Sci U S A. 2022 Oct 4;119(40):e2204828119. doi: 10.1073/pnas.2204828119. Epub 2022 Sep 26. Proc Natl Acad Sci U S A. 2022. PMID: 36161942 Free PMC article.
β-Arrestin2 arrests the clearance of tau in FTLD.
Thathiah A. Thathiah A. Proc Natl Acad Sci U S A. 2020 Mar 31;117(13):6968-6970. doi: 10.1073/pnas.2001455117. Epub 2020 Mar 18. Proc Natl Acad Sci U S A. 2020. PMID: 32188777 Free PMC article. No abstract available.
RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43.
Mann JR, Gleixner AM, Mauna JC, Gomes E, DeChellis-Marks MR, Needham PG, Copley KE, Hurtle B, Portz B, Pyles NJ, Guo L, Calder CB, Wills ZP, Pandey UB, Kofler JK, Brodsky JL, Thathiah A, Shorter J, Donnelly CJ. Mann JR, et al. Among authors: thathiah a. Neuron. 2019 Apr 17;102(2):321-338.e8. doi: 10.1016/j.neuron.2019.01.048. Epub 2019 Feb 27. Neuron. 2019. PMID: 30826182 Free PMC article.
29 results