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Plasma brain-derived tau is an amyloid-associated neurodegeneration biomarker in Alzheimer's disease.
Gonzalez-Ortiz F, Kirsebom BE, Contador J, Tanley JE, Selnes P, Gísladóttir B, Pålhaugen L, Suhr Hemminghyth M, Jarholm J, Skogseth R, Bråthen G, Grøndtvedt G, Bjørnerud A, Tecelao S, Waterloo K, Aarsland D, Fernández-Lebrero A, García-Escobar G, Navalpotro-Gómez I, Turton M, Hesthamar A, Kac PR, Nilsson J, Luchsinger J, Hayden KM, Harrison P, Puig-Pijoan A, Zetterberg H, Hughes TM, Suárez-Calvet M, Karikari TK, Fladby T, Blennow K. Gonzalez-Ortiz F, et al. Among authors: karikari tk. Nat Commun. 2024 Apr 4;15(1):2908. doi: 10.1038/s41467-024-47286-5. Nat Commun. 2024. PMID: 38575616 Free PMC article.
Preanalytical stability of plasma/serum brain-derived tau.
Gonzalez-Ortiz F, Dias A, Turton M, Magalhães R, Kac PR, Correia M, Harrison P, Zetterberg H, Maia LF, Blennow K, Karikari TK. Gonzalez-Ortiz F, et al. Among authors: karikari tk. Alzheimers Dement. 2023 Oct;19(10):4764-4770. doi: 10.1002/alz.13156. Epub 2023 May 26. Alzheimers Dement. 2023. PMID: 37232524
Plasma p-tau212 antemortem diagnostic performance and prediction of autopsy verification of Alzheimer's disease neuropathology.
Kac PR, González-Ortiz F, Emeršič A, Dulewicz M, Koutarapu S, Turton M, An Y, Smirnov D, Kulczyńska-Przybik A, Varma VR, Ashton NJ, Montoliu-Gaya L, Camporesi E, Winkel I, Paradowski B, Moghekar A, Troncoso JC, Lashley T, Brinkmalm G, Resnick SM, Mroczko B, Kvartsberg H, Gregorič Kramberger M, Hanrieder J, Čučnik S, Harrison P, Zetterberg H, Lewczuk P, Thambisetty M, Rot U, Galasko D, Blennow K, Karikari TK. Kac PR, et al. Among authors: karikari tk. Nat Commun. 2024 Mar 23;15(1):2615. doi: 10.1038/s41467-024-46876-7. Nat Commun. 2024. PMID: 38521766 Free PMC article.
Levels of plasma brain-derived tau and p-tau181 in Alzheimer's disease and rapidly progressive dementias.
Gonzalez-Ortiz F, Karikari TK, Bentivenga GM, Baiardi S, Mammana A, Turton M, Kac PR, Mastrangelo A, Harrison P, Capellari S, Zetterberg H, Blennow K, Parchi P. Gonzalez-Ortiz F, et al. Among authors: karikari tk. Alzheimers Dement. 2024 Jan;20(1):745-751. doi: 10.1002/alz.13516. Epub 2023 Oct 19. Alzheimers Dement. 2024. PMID: 37858957 Free PMC article.
An update on blood-based biomarkers for non-Alzheimer neurodegenerative disorders.
Ashton NJ, Hye A, Rajkumar AP, Leuzy A, Snowden S, Suárez-Calvet M, Karikari TK, Schöll M, La Joie R, Rabinovici GD, Höglund K, Ballard C, Hortobágyi T, Svenningsson P, Blennow K, Zetterberg H, Aarsland D. Ashton NJ, et al. Among authors: karikari tk. Nat Rev Neurol. 2020 May;16(5):265-284. doi: 10.1038/s41582-020-0348-0. Epub 2020 Apr 22. Nat Rev Neurol. 2020. PMID: 32322100 Review.
Plasma p-tau181 accurately predicts Alzheimer's disease pathology at least 8 years prior to post-mortem and improves the clinical characterisation of cognitive decline.
Lantero Rodriguez J, Karikari TK, Suárez-Calvet M, Troakes C, King A, Emersic A, Aarsland D, Hye A, Zetterberg H, Blennow K, Ashton NJ. Lantero Rodriguez J, et al. Among authors: karikari tk. Acta Neuropathol. 2020 Sep;140(3):267-278. doi: 10.1007/s00401-020-02195-x. Epub 2020 Jul 27. Acta Neuropathol. 2020. PMID: 32720099 Free PMC article.
Association between polygenic risk score of Alzheimer's disease and plasma phosphorylated tau in individuals from the Alzheimer's Disease Neuroimaging Initiative.
Zettergren A, Lord J, Ashton NJ, Benedet AL, Karikari TK, Lantero Rodriguez J; Alzheimer’s Disease Neuroimaging Initiative*; Snellman A, Suárez-Calvet M, Proitsi P, Zetterberg H, Blennow K. Zettergren A, et al. Among authors: karikari tk. Alzheimers Res Ther. 2021 Jan 8;13(1):17. doi: 10.1186/s13195-020-00754-8. Alzheimers Res Ther. 2021. PMID: 33419453 Free PMC article.
Effects of pre-analytical procedures on blood biomarkers for Alzheimer's pathophysiology, glial activation, and neurodegeneration.
Ashton NJ, Suárez-Calvet M, Karikari TK, Lantero-Rodriguez J, Snellman A, Sauer M, Simrén J, Minguillon C, Fauria K, Blennow K, Zetterberg H. Ashton NJ, et al. Among authors: karikari tk. Alzheimers Dement (Amst). 2021 Jun 2;13(1):e12168. doi: 10.1002/dad2.12168. eCollection 2021. Alzheimers Dement (Amst). 2021. PMID: 34124336 Free PMC article.
Phosphorylated tau181 in plasma as a potential biomarker for Alzheimer's disease in adults with Down syndrome.
Lleó A, Zetterberg H, Pegueroles J, Karikari TK, Carmona-Iragui M, Ashton NJ, Montal V, Barroeta I, Lantero-Rodríguez J, Videla L, Altuna M, Benejam B, Fernandez S, Valldeneu S, Garzón D, Bejanin A, Iulita MF, Camacho V, Medrano-Martorell S, Belbin O, Clarimon J, Lehmann S, Alcolea D, Blesa R, Blennow K, Fortea J. Lleó A, et al. Among authors: karikari tk. Nat Commun. 2021 Jul 14;12(1):4304. doi: 10.1038/s41467-021-24319-x. Nat Commun. 2021. PMID: 34262030 Free PMC article.
158 results