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Vasorelaxant and hypotensive effects of an ethanolic extract of Nymphaea pubescens and its main compound quercetin 3-methyl ether 3'-O-β-xylopyranoside.
Panklai T, Ingkaninan K, Chootip K, Temkitthawon P, Suphrom N, Tournier-Nappey M, Girard C, Demougeot C, Totoson P. Panklai T, et al. Among authors: ingkaninan k. Front Pharmacol. 2024 Mar 21;15:1379752. doi: 10.3389/fphar.2024.1379752. eCollection 2024. Front Pharmacol. 2024. PMID: 38576494 Free PMC article.
The new quinazoline derivative (N2-methyl-N4-[(thiophen-2-yl)methyl]quinazoline-2,4-diamine) vasodilates isolated mesenteric arteries through endothelium-independent mechanisms and has acute hypotensive effects in Wistar rats.
Chatturong U, Chootip K, Martin H, Tournier-Nappey M, Ingkaninan K, Temkitthawon P, Sermsenaphorn S, Somarin T, Konsue A, Gleeson MP, Totoson P, Demougeot C. Chatturong U, et al. Among authors: ingkaninan k. Eur J Pharmacol. 2023 Aug 15;953:175829. doi: 10.1016/j.ejphar.2023.175829. Epub 2023 Jun 10. Eur J Pharmacol. 2023. PMID: 37307938
Quinazoline-based human phosphodiesterase 5 inhibitors exhibited a selective vasorelaxant effect on rat isolated pulmonary arteries involving NO-sGC-cGMP pathway and calcium inhibitory effects.
Chatturong U, Martin H, Totoson P, Ingkaninan K, Temkitthawon P, Sermsenaphorn S, Somarin T, Konsue A, Gleeson MP, Demougeot C, Chootip K. Chatturong U, et al. Among authors: ingkaninan k. Vascul Pharmacol. 2022 Dec;147:107111. doi: 10.1016/j.vph.2022.107111. Epub 2022 Sep 24. Vascul Pharmacol. 2022. PMID: 36162651
Curcumin analogues inhibit phosphodiesterase-5 and dilate rat pulmonary arteries.
Kruangtip O, Chootip K, Temkitthawon P, Changwichit K, Chuprajob T, Changtam C, Suksamrarn A, Khorana N, Scholfield CN, Ingkaninan K. Kruangtip O, et al. Among authors: ingkaninan k. J Pharm Pharmacol. 2015 Jan;67(1):87-95. doi: 10.1111/jphp.12302. Epub 2014 Sep 1. J Pharm Pharmacol. 2015. PMID: 25176340
Elucidation of Vasodilation Response and Structure Activity Relationships of N²,N⁴-Disubstituted Quinazoline 2,4-Diamines in a Rat Pulmonary Artery Model.
Paracha TU, Pobsuk N, Salaloy N, Suphakun P, Pekthong D, Hannongbua S, Choowongkomon K, Khorana N, Temkitthawon P, Ingkaninan K, Gleeson MP, Chootip K. Paracha TU, et al. Among authors: ingkaninan k. Molecules. 2019 Jan 14;24(2):281. doi: 10.3390/molecules24020281. Molecules. 2019. PMID: 30646523 Free PMC article.
131 results