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Antascomicin B stabilizes FKBP51-Akt1 complexes as a molecular glue.
Schäfer SC, Voll AM, Bracher A, Ley SV, Hausch F. Schäfer SC, et al. Among authors: ley sv. Bioorg Med Chem Lett. 2024 May 15;104:129728. doi: 10.1016/j.bmcl.2024.129728. Epub 2024 Apr 4. Bioorg Med Chem Lett. 2024. PMID: 38582133 Free article.
Continuous flow synthesis enabling reaction discovery.
Alfano AI, García-Lacuna J, Griffiths OM, Ley SV, Baumann M. Alfano AI, et al. Among authors: ley sv. Chem Sci. 2024 Feb 28;15(13):4618-4630. doi: 10.1039/d3sc06808k. eCollection 2024 Mar 27. Chem Sci. 2024. PMID: 38550700 Free PMC article. Review.
Nitro-sulfinate Reductive Coupling to Access (Hetero)aryl Sulfonamides.
Gatarz SE, Griffiths OM, Esteves HA, Jiao W, Morse P, Fisher EL, Blakemore DC, Ley SV. Gatarz SE, et al. Among authors: ley sv. J Org Chem. 2024 Feb 2;89(3):1898-1909. doi: 10.1021/acs.joc.3c02557. Epub 2024 Jan 18. J Org Chem. 2024. PMID: 38239107 Free PMC article.
292 results