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Systemic inflammation, the peripheral blood transcriptome and primary melanoma.
Randerson-Moor J, Davies J, Harland M, Nsengimana J, Bigirumurame T, Walker C, Laye J, Appleton ES, Ball G, Cook GP, Bishop DT, Salmond RJ, Newton-Bishop J. Randerson-Moor J, et al. Among authors: appleton es. J Invest Dermatol. 2024 Apr 5:S0022-202X(24)00275-6. doi: 10.1016/j.jid.2024.02.034. Online ahead of print. J Invest Dermatol. 2024. PMID: 38583742 Free article.
Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade.
Samson A, Scott KJ, Taggart D, West EJ, Wilson E, Nuovo GJ, Thomson S, Corns R, Mathew RK, Fuller MJ, Kottke TJ, Thompson JM, Ilett EJ, Cockle JV, van Hille P, Sivakumar G, Polson ES, Turnbull SJ, Appleton ES, Migneco G, Rose AS, Coffey MC, Beirne DA, Collinson FJ, Ralph C, Alan Anthoney D, Twelves CJ, Furness AJ, Quezada SA, Wurdak H, Errington-Mais F, Pandha H, Harrington KJ, Selby PJ, Vile RG, Griffin SD, Stead LF, Short SC, Melcher AA. Samson A, et al. Among authors: appleton es. Sci Transl Med. 2018 Jan 3;10(422):eaam7577. doi: 10.1126/scitranslmed.aam7577. Sci Transl Med. 2018. PMID: 29298869 Free PMC article.
Talimogene laherparepvec in the treatment of melanoma.
Appleton ES, Turnbull S, Ralph C, West E, Scott K, Harrington K, Pandha H, Melcher A. Appleton ES, et al. Expert Opin Biol Ther. 2015;15(10):1517-30. doi: 10.1517/14712598.2015.1084280. Expert Opin Biol Ther. 2015. PMID: 26629575 Review.