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A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death.
Mannion J, Gifford V, Bellenie B, Fernando W, Ramos Garcia L, Wilson R, John SW, Udainiya S, Patin EC, Tiu C, Smith A, Goicoechea M, Craxton A, Moraes de Vasconcelos N, Guppy N, Cheung KJ, Cundy NJ, Pierrat O, Brennan A, Roumeliotis TI, Benstead-Hume G, Alexander J, Muirhead G, Layzell S, Lyu W, Roulstone V, Allen M, Baldock H, Legrand A, Gabel F, Serrano-Aparicio N, Starling C, Guo H, Upton J, Gyrd-Hansen M, MacFarlane M, Seddon B, Raynaud F, Roxanis I, Harrington K, Haider S, Choudhary JS, Hoelder S, Tenev T, Meier P. Mannion J, et al. Among authors: udainiya s. Immunity. 2024 May 15:S1074-7613(24)00230-9. doi: 10.1016/j.immuni.2024.04.025. Online ahead of print. Immunity. 2024. PMID: 38788712
A complement C4-derived glycopeptide is a biomarker for PMM2-CDG.
Garapati K, Budhraja R, Saraswat M, Kim J, Joshi N, Sachdeva GS, Jain A, Ligezka AN, Radenkovic S, Ramarajan MG, Udainiya S, Raymond K, He M, Lam C, Larson A, Edmondson AC, Sarafoglou K, Larson NB, Freeze HH, Schultz MJ, Kozicz T, Morava E, Pandey A. Garapati K, et al. Among authors: udainiya s. JCI Insight. 2024 Apr 8;9(7):e172509. doi: 10.1172/jci.insight.172509. JCI Insight. 2024. PMID: 38587076 Free PMC article.
Tyrosine Phosphoproteomics of Patient-Derived Xenografts Reveals Ephrin Type-B Receptor 4 Tyrosine Kinase as a Therapeutic Target in Pancreatic Cancer.
Renuse S, Madamsetty VS, Mun DG, Madugundu AK, Singh S, Udainiya S, Mangalaparthi KK, Kim MS, Liu R, Kumar SR, Krasnoperov V, Truty M, Graham RP, Gill PS, Mukhopadhyay D, Pandey A. Renuse S, et al. Among authors: udainiya s. Cancers (Basel). 2021 Jul 7;13(14):3404. doi: 10.3390/cancers13143404. Cancers (Basel). 2021. PMID: 34298619 Free PMC article.
PASS-DIA: A Data-Independent Acquisition Approach for Discovery Studies.
Mun DG, Renuse S, Saraswat M, Madugundu A, Udainiya S, Kim H, Park SR, Zhao H, Nirujogi RS, Na CH, Kannan N, Yates JR 3rd, Lee SW, Pandey A. Mun DG, et al. Among authors: udainiya s. Anal Chem. 2020 Nov 3;92(21):14466-14475. doi: 10.1021/acs.analchem.0c02513. Epub 2020 Oct 20. Anal Chem. 2020. PMID: 33079518