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Page 1
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer.
Wasko UN, Jiang J, Dalton TC, Curiel-Garcia A, Edwards AC, Wang Y, Lee B, Orlen M, Tian S, Stalnecker CA, Drizyte-Miller K, Menard M, Dilly J, Sastra SA, Palermo CF, Hasselluhn MC, Decker-Farrell AR, Chang S, Jiang L, Wei X, Yang YC, Helland C, Courtney H, Gindin Y, Muonio K, Zhao R, Kemp SB, Clendenin C, Sor R, Vostrejs WP, Hibshman PS, Amparo AM, Hennessey C, Rees MG, Ronan MM, Roth JA, Brodbeck J, Tomassoni L, Bakir B, Socci ND, Herring LE, Barker NK, Wang J, Cleary JM, Wolpin BM, Chabot JA, Kluger MD, Manji GA, Tsai KY, Sekulic M, Lagana SM, Califano A, Quintana E, Wang Z, Smith JAM, Holderfield M, Wildes D, Lowe SW, Badgley MA, Aguirre AJ, Vonderheide RH, Stanger BZ, Baslan T, Der CJ, Singh M, Olive KP. Wasko UN, et al. Among authors: brodbeck j. Nature. 2024 May;629(8013):927-936. doi: 10.1038/s41586-024-07379-z. Epub 2024 Apr 8. Nature. 2024. PMID: 38588697 Free PMC article.
The operational environment and rotational acceleration of asteroid (101955) Bennu from OSIRIS-REx observations.
Hergenrother CW, Maleszewski CK, Nolan MC, Li JY, Drouet d'Aubigny CY, Shelly FC, Howell ES, Kareta TR, Izawa MRM, Barucci MA, Bierhaus EB, Campins H, Chesley SR, Clark BE, Christensen EJ, DellaGiustina DN, Fornasier S, Golish DR, Hartzell CM, Rizk B, Scheeres DJ, Smith PH, Zou XD, Lauretta DS; OSIRIS-REx Team. Hergenrother CW, et al. Nat Commun. 2019 Mar 19;10(1):1291. doi: 10.1038/s41467-019-09213-x. Nat Commun. 2019. PMID: 30890725 Free PMC article.
Selective depletion of HBV-infected hepatocytes by class A capsid assembly modulators requires high levels of intrahepatic HBV core protein.
Kornyeyev D, Song Z, Eng S, Soulette C, Ramirez R, Tang J, Yue Q, Subramanian R, Zaboli S, Moon C, Tam J, Brodbeck J, Aggarwal A, Diehl L, Fletcher SP, Hyrina A, Holdorf MM, Burdette D. Kornyeyev D, et al. Among authors: brodbeck j. Antimicrob Agents Chemother. 2024 May 23:e0042024. doi: 10.1128/aac.00420-24. Online ahead of print. Antimicrob Agents Chemother. 2024. PMID: 38780261 Free article.
Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers.
Jiang J, Jiang L, Maldonato BJ, Wang Y, Holderfield M, Aronchik I, Winters IP, Salman Z, Blaj C, Menard M, Brodbeck J, Chen Z, Wei X, Rosen MJ, Gindin Y, Lee BJ, Evans JW, Chang S, Wang Z, Seamon KJ, Parsons D, Cregg J, Marquez A, Tomlinson ACA, Yano JK, Knox JE, Quintana E, Aguirre AJ, Arbour KC, Reed A, Gustafson WC, Gill AL, Koltun ES, Wildes D, Smith JAM, Wang Z, Singh M. Jiang J, et al. Among authors: brodbeck j. Cancer Discov. 2024 Jun 3;14(6):994-1017. doi: 10.1158/2159-8290.CD-24-0027. Cancer Discov. 2024. PMID: 38593348
Intrahepatic quantification of HBV antigens in chronic hepatitis B reveals heterogeneity and treatment-mediated reductions in HBV core-positive cells.
Aggarwal A, Odorizzi PM, Brodbeck J, van Buuren N, Moon C, Chang S, Adona M, Suthram S, Suri V, Trowe T, Turner S, Marcellin P, Buti M, Gaggar A, Fletcher SP, Diehl L, Feierbach B, Balsitis S. Aggarwal A, et al. Among authors: brodbeck j. JHEP Rep. 2022 Dec 26;5(4):100664. doi: 10.1016/j.jhepr.2022.100664. eCollection 2023 Apr. JHEP Rep. 2022. PMID: 36908748 Free PMC article.
65 results