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Haploinsufficiency of phosphodiesterase 10A activates PI3K/AKT signaling independent of PTEN to induce an aggressive glioma phenotype.
Nuechterlein N, Shelbourn A, Szulzewsky F, Arora S, Casad M, Pattwell S, Merino-Galan L, Sulman E, Arowa S, Alvinez N, Jung M, Brown D, Tang K, Jackson S, Stoica S, Chittaboina P, Banasavadi-Siddegowda YK, Wirsching HG, Stella N, Shapiro L, Paddison P, Patel AP, Gilbert MR, Abdullaev Z, Aldape K, Pratt D, Holland EC, Cimino PJ. Nuechterlein N, et al. Among authors: alvinez n. Genes Dev. 2024 Apr 17;38(5-6):273-288. doi: 10.1101/gad.351350.123. Genes Dev. 2024. PMID: 38589034
ERK signaling promotes resistance to TRK kinase inhibition in NTRK fusion-driven glioma mouse models.
Schmid S, Russell ZR, Yamashita AS, West ME, Parrish AG, Walker J, Rudoy D, Yan JZ, Quist DC, Gessesse BN, Alvinez N, Cimino PJ, Kumasaka DK, Parchment RE, Holland EC, Szulzewsky F. Schmid S, et al. Among authors: alvinez n. bioRxiv [Preprint]. 2024 Mar 26:2024.03.13.584849. doi: 10.1101/2024.03.13.584849. bioRxiv. 2024. PMID: 38558981 Free PMC article. Preprint.
A Fiji process for quantifying fluorescent puncta in linear cellular structures.
Hulsey-Vincent H, Alvinez N, Witus S, Kowalski JR, Dahlberg C. Hulsey-Vincent H, et al. Among authors: alvinez n. MicroPubl Biol. 2023 Dec 14;2023:10.17912/micropub.biology.001003. doi: 10.17912/micropub.biology.001003. eCollection 2023. MicroPubl Biol. 2023. PMID: 38170046 Free PMC article.