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Haploinsufficiency of phosphodiesterase 10A activates PI3K/AKT signaling independent of PTEN to induce an aggressive glioma phenotype.
Nuechterlein N, Shelbourn A, Szulzewsky F, Arora S, Casad M, Pattwell S, Merino-Galan L, Sulman E, Arowa S, Alvinez N, Jung M, Brown D, Tang K, Jackson S, Stoica S, Chittaboina P, Banasavadi-Siddegowda YK, Wirsching HG, Stella N, Shapiro L, Paddison P, Patel AP, Gilbert MR, Abdullaev Z, Aldape K, Pratt D, Holland EC, Cimino PJ. Nuechterlein N, et al. Among authors: jackson s. Genes Dev. 2024 Apr 17;38(5-6):273-288. doi: 10.1101/gad.351350.123. Genes Dev. 2024. PMID: 38589034
Targeting WNT Signaling for Multifaceted Glioblastoma Therapy.
McCord M, Mukouyama YS, Gilbert MR, Jackson S. McCord M, et al. Among authors: jackson s. Front Cell Neurosci. 2017 Oct 13;11:318. doi: 10.3389/fncel.2017.00318. eCollection 2017. Front Cell Neurosci. 2017. PMID: 29081735 Free PMC article. Review.
Ibrutinib disrupts blood-tumor barrier integrity and prolongs survival in rodent glioma model.
Lim S, Kwak M, Kang J, Cesaire M, Tang K, Robey RW, Frye WJE, Karim B, Butcher D, Lizak MJ, Dalmage M, Foster B, Nuechterlein N, Eberhart C, Cimino PJ, Gottesman MM, Jackson S. Lim S, et al. Among authors: jackson s. Acta Neuropathol Commun. 2024 Apr 8;12(1):56. doi: 10.1186/s40478-024-01763-6. Acta Neuropathol Commun. 2024. PMID: 38589905 Free PMC article.
Adenosine A2A Receptor Activation Enhances Blood-Tumor Barrier Permeability in a Rodent Glioma Model.
Vézina A, Manglani M, Morris D, Foster B, McCord M, Song H, Zhang M, Davis D, Zhang W, Bills J, Nagashima K, Shankarappa P, Kindrick J, Walbridge S, Peer CJ, Figg WD, Gilbert MR, McGavern DB, Muldoon LL, Jackson S. Vézina A, et al. Among authors: jackson s. Mol Cancer Res. 2021 Dec;19(12):2081-2095. doi: 10.1158/1541-7786.MCR-19-0995. Epub 2021 Sep 14. Mol Cancer Res. 2021. PMID: 34521765 Free PMC article.
Inhibiting protein phosphatase 2A increases the antitumor effect of protein arginine methyltransferase 5 inhibition in models of glioblastoma.
Otani Y, Sur HP, Rachaiah G, Namagiri S, Chowdhury A, Lewis CT, Shimizu T, Gangaplara A, Wang X, Vézina A, Maric D, Jackson S, Yan Y, Zhengping Z, Ray-Chaudhury A, Kumar S, Ballester LY, Chittiboina P, Yoo JY, Heiss J, Kaur B, Banasavadi-Siddegowda YK. Otani Y, et al. Among authors: jackson s. Neuro Oncol. 2021 Sep 1;23(9):1481-1493. doi: 10.1093/neuonc/noab014. Neuro Oncol. 2021. PMID: 33556161 Free PMC article.
Cytokine Microdialysis for Real-Time Immune Monitoring in Glioblastoma Patients Undergoing Checkpoint Blockade.
Lynes J, Jackson S, Sanchez V, Dominah G, Wang X, Kuek A, Hayes CP, Benzo S, Scott GC, Chittiboina P, Zaghloul KA, Park DM, Wu J, Hourigan CS, Giles AJ, Wu T, Maric D, Chen J, Quezado M, Heiss JD, Gilbert MR, Nduom EK. Lynes J, et al. Among authors: jackson s. Neurosurgery. 2019 Apr 1;84(4):945-953. doi: 10.1093/neuros/nyy392. Neurosurgery. 2019. PMID: 30189044 Free PMC article. Clinical Trial.
4,699 results