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Identification of kinase modulators as host-directed therapeutics against intracellular methicillin-resistant Staphylococcus aureus.
van den Biggelaar RHGA, Walburg KV, van den Eeden SJF, van Doorn CLR, Meiler E, de Ries AS, Meijer AH, Ottenhoff THM, Saris A. van den Biggelaar RHGA, et al. Among authors: van den eeden sjf. Front Cell Infect Microbiol. 2024 Mar 25;14:1367938. doi: 10.3389/fcimb.2024.1367938. eCollection 2024. Front Cell Infect Microbiol. 2024. PMID: 38590439 Free PMC article.
The in vivo expressed Mycobacterium tuberculosis (IVE-TB) antigen Rv2034 induces CD4⁺ T-cells that protect against pulmonary infection in HLA-DR transgenic mice and guinea pigs.
Commandeur S, van den Eeden SJ, Dijkman K, Clark SO, van Meijgaarden KE, Wilson L, Franken KL, Williams A, Christensen D, Ottenhoff TH, Geluk A. Commandeur S, et al. Vaccine. 2014 Jun 17;32(29):3580-8. doi: 10.1016/j.vaccine.2014.05.005. Epub 2014 May 14. Vaccine. 2014. PMID: 24837764
Clonal analysis of the T-cell response to in vivo expressed Mycobacterium tuberculosis protein Rv2034, using a CD154 expression based T-cell cloning method.
Commandeur S, Coppola M, Dijkman K, Friggen AH, van Meijgaarden KE, van den Eeden SJ, Wilson L, van der Ploeg-van Schip JJ, Franken KL, Geluk A, Ottenhoff TH. Commandeur S, et al. PLoS One. 2014 Jun 6;9(6):e99203. doi: 10.1371/journal.pone.0099203. eCollection 2014. PLoS One. 2014. PMID: 24905579 Free PMC article.
Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1.
Kuijl C, Savage ND, Marsman M, Tuin AW, Janssen L, Egan DA, Ketema M, van den Nieuwendijk R, van den Eeden SJ, Geluk A, Poot A, van der Marel G, Beijersbergen RL, Overkleeft H, Ottenhoff TH, Neefjes J. Kuijl C, et al. Nature. 2007 Nov 29;450(7170):725-30. doi: 10.1038/nature06345. Nature. 2007. PMID: 18046412
36 results