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Clusterin deficiency is associated with a lack of response to teriflunomide in multiple sclerosis.
Malhotra S, Fissolo N, Rodríguez-Rivera C, Monreal E, Montpeyo M, Urcelay E, Triviño JC, Pérez-García MJ, Segura MF, Pappolla A, Río J, Vilaseca A, Fernández Velasco JI, Miguez A, Goicoechea C, Martinez-Vicente M, Villar LM, Montalban X, Comabella M. Malhotra S, et al. Among authors: segura mf. Clin Transl Med. 2024 Apr;14(4):e1654. doi: 10.1002/ctm2.1654. Clin Transl Med. 2024. PMID: 38591764 Free PMC article. No abstract available.
FAIM Is Regulated by MiR-206, MiR-1-3p and MiR-133b.
Coccia E, Masanas M, López-Soriano J, Segura MF, Comella JX, Pérez-García MJ. Coccia E, et al. Among authors: segura mf. Front Cell Dev Biol. 2020 Dec 23;8:584606. doi: 10.3389/fcell.2020.584606. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 33425889 Free PMC article.
SIVA-1 regulates apoptosis and synaptic function by modulating XIAP interaction with the death receptor antagonist FAIM-L.
Coccia E, Planells-Ferrer L, Badillos-Rodríguez R, Pascual M, Segura MF, Fernández-Hernández R, López-Soriano J, Garí E, Soriano E, Barneda-Zahonero B, Moubarak RS, Pérez-García MJ, Comella JX. Coccia E, et al. Among authors: segura mf. Cell Death Dis. 2020 Feb 3;11(2):82. doi: 10.1038/s41419-020-2282-x. Cell Death Dis. 2020. PMID: 32015347 Free PMC article.
The death receptor antagonist FLIP-L interacts with Trk and is necessary for neurite outgrowth induced by neurotrophins.
Moubarak RS, Solé C, Pascual M, Gutierrez H, Llovera M, Pérez-García MJ, Gozzelino R, Segura MF, Iglesias-Guimarais V, Reix S, Soler RM, Davies AM, Soriano E, Yuste VJ, Comella JX. Moubarak RS, et al. Among authors: segura mf. J Neurosci. 2010 Apr 28;30(17):6094-105. doi: 10.1523/JNEUROSCI.0537-10.2010. J Neurosci. 2010. PMID: 20427667 Free PMC article.
The long form of Fas apoptotic inhibitory molecule is expressed specifically in neurons and protects them against death receptor-triggered apoptosis.
Segura MF, Sole C, Pascual M, Moubarak RS, Perez-Garcia MJ, Gozzelino R, Iglesias V, Badiola N, Bayascas JR, Llecha N, Rodriguez-Alvarez J, Soriano E, Yuste VJ, Comella JX. Segura MF, et al. J Neurosci. 2007 Oct 17;27(42):11228-41. doi: 10.1523/JNEUROSCI.3462-07.2007. J Neurosci. 2007. PMID: 17942717 Free PMC article.
The oral KIF11 inhibitor 4SC-205 exhibits antitumor activity and potentiates standard and targeted therapies in primary and metastatic neuroblastoma models.
Masanas M, Masiá N, Suárez-Cabrera L, Olivan M, Soriano A, Majem B, Devis-Jauregui L, Burgos-Panadero R, Jiménez C, Rodriguez-Sodupe P, Boloix A, Toledano I, Guillén G, Navarro A, Llobet-Navas D, Villanueva A, Sánchez de Toledo J, Roma J, Noguera R, Moreno L, Krauss R, Gallego S, Santamaria A, Segura MF. Masanas M, et al. Among authors: segura mf. Clin Transl Med. 2021 Oct;11(10):e533. doi: 10.1002/ctm2.533. Clin Transl Med. 2021. PMID: 34709738 Free PMC article. No abstract available.
BCL-XL regulates TNF-alpha-mediated cell death independently of NF-kappaB, FLIP and IAPs.
Gozzelino R, Sole C, Llecha N, Segura MF, Moubarak RS, Iglesias-Guimarais V, Perez-Garcia MJ, Reix S, Zhang J, Badiola N, Sanchis D, Rodriguez-Alvarez J, Trullas R, Yuste VJ, Comella JX. Gozzelino R, et al. Among authors: segura mf. Cell Res. 2008 Oct;18(10):1020-36. doi: 10.1038/cr.2008.76. Cell Res. 2008. PMID: 18591962
Targeting the Hedgehog Pathway in Rhabdomyosarcoma.
Zarzosa P, Garcia-Gilabert L, Hladun R, Guillén G, Gallo-Oller G, Pons G, Sansa-Girona J, Segura MF, Sánchez de Toledo J, Moreno L, Gallego S, Roma J. Zarzosa P, et al. Among authors: segura mf. Cancers (Basel). 2023 Jan 24;15(3):727. doi: 10.3390/cancers15030727. Cancers (Basel). 2023. PMID: 36765685 Free PMC article. Review.
79 results