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Schiff bases and their metal complexes to target and overcome (multidrug) resistance in cancer.
Eur J Med Chem. 2024 Apr 15;270:116363. doi: 10.1016/j.ejmech.2024.116363. Epub 2024 Mar 29.
Eur J Med Chem. 2024.
PMID: 38593587
Review.
Cancer Cell Resistance Against the Clinically Investigated Thiosemicarbazone COTI-2 Is Based on Formation of Intracellular Copper Complex Glutathione Adducts and ABCC1-Mediated Efflux.
Bormio Nunes JH, Hager S, Mathuber M, Pósa V, Roller A, Enyedy ÉA, Stefanelli A, Berger W, Keppler BK, Heffeter P, Kowol CR.
Bormio Nunes JH, et al.
J Med Chem. 2020 Nov 25;63(22):13719-13732. doi: 10.1021/acs.jmedchem.0c01277. Epub 2020 Nov 15.
J Med Chem. 2020.
PMID: 33190481
Free PMC article.
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New findings on the antiproliferative activity of the silver(I) complex with 5-fluorouracil against human multi-resistant NCI/ADR-RES ovarian tumor cells.
Bormio Nunes JH, de Paiva PP, Ruiz ALTG, de Carvalho JE, Corbi PP.
Bormio Nunes JH, et al.
Toxicol In Vitro. 2019 Oct;60:359-368. doi: 10.1016/j.tiv.2019.06.018. Epub 2019 Jun 22.
Toxicol In Vitro. 2019.
PMID: 31238103
Free article.
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