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Comprehensive Characterization of a Systematic Library of Alkyl and Alicyclic Synthetic Cannabinoids Related to CUMYL-PICA, CUMYL-BUTICA, CUMYL-CBMICA, and CUMYL-PINACA.
Janssens LK, Ametovski A, Sparkes E, Boyd R, Lai F, Maloney CJ, Rhook D, Gerona RR, Connolly M, Liu H, Hibbs DE, Cairns EA, Banister SD, Stove CP. Janssens LK, et al. Among authors: cairns ea. ACS Chem Neurosci. 2023 Jan 4;14(1):35-52. doi: 10.1021/acschemneuro.2c00408. Epub 2022 Dec 18. ACS Chem Neurosci. 2023. PMID: 36530139
Structure-Activity Relationships, Deuteration, and Fluorination of Synthetic Cannabinoid Receptor Agonists Related to AKB48, 5F-AKB-48, and AFUBIATA.
Sparkes E, Maloney CJ, Markham JW, Dane C, Boyd R, Gilchrist J, Moir M, Gordon R, Luo JL, Pike E, Walker KA, Kassiou M, McGregor IS, Kevin RC, Hibbs DE, Jorgensen WT, Banister SD, Cairns EA, Ametovski A. Sparkes E, et al. Among authors: cairns ea. ACS Chem Neurosci. 2024 May 20. doi: 10.1021/acschemneuro.3c00850. Online ahead of print. ACS Chem Neurosci. 2024. PMID: 38766866
Synthesis and pharmacological evaluation of newly detected synthetic cannabinoid receptor agonists AB-4CN-BUTICA, MMB-4CN-BUTINACA, MDMB-4F-BUTICA, MDMB-4F-BUTINACA and their analogs.
Sparkes E, Boyd R, Chen S, Markham JW, Luo JL, Foyzun T, Zaman H, Fletcher C, Ellison R, McGregor IS, Santiago MJ, Lai F, Gerona RR, Connor M, Hibbs DE, Cairns EA, Glass M, Ametovski A, Banister SD. Sparkes E, et al. Among authors: cairns ea. Front Psychiatry. 2022 Sep 28;13:1010501. doi: 10.3389/fpsyt.2022.1010501. eCollection 2022. Front Psychiatry. 2022. PMID: 36245876 Free PMC article.
Putative Synthetic Cannabinoids MEPIRAPIM, 5F-BEPIRAPIM (NNL-2), and Their Analogues Are T-Type Calcium Channel (CaV3) Inhibitors.
Kevin RC, Mirlohi S, Manning JJ, Boyd R, Cairns EA, Ametovski A, Lai F, Luo JL, Jorgensen W, Ellison R, Gerona RR, Hibbs DE, McGregor IS, Glass M, Connor M, Bladen C, Zamponi GW, Banister SD. Kevin RC, et al. Among authors: cairns ea. ACS Chem Neurosci. 2022 May 4;13(9):1395-1409. doi: 10.1021/acschemneuro.1c00822. Epub 2022 Apr 20. ACS Chem Neurosci. 2022. PMID: 35442021
Structure-activity relationships of valine, tert-leucine, and phenylalanine amino acid-derived synthetic cannabinoid receptor agonists related to ADB-BUTINACA, APP-BUTINACA, and ADB-P7AICA.
Sparkes E, Cairns EA, Kevin RC, Lai F, Grafinger KE, Chen S, Deventer MH, Ellison R, Boyd R, Martin LJ, McGregor IS, Gerona RR, Hibbs DE, Auwärter V, Glass M, Stove C, Banister SD. Sparkes E, et al. Among authors: cairns ea. RSC Med Chem. 2021 Oct 25;13(2):156-174. doi: 10.1039/d1md00242b. eCollection 2022 Feb 23. RSC Med Chem. 2021. PMID: 35308023 Free PMC article.
NNL-3: A Synthetic Intermediate or a New Class of Hydroxybenzotriazole Esters with Cannabinoid Receptor Activity?
Ametovski A, Cairns EA, Grafinger KE, Cannaert A, Deventer MH, Chen S, Wu X, Shepperson CE, Lai F, Ellison R, Gerona R, Blakey K, Kevin R, McGregor IS, Hibbs DE, Glass M, Stove C, Auwärter V, Banister SD. Ametovski A, et al. Among authors: cairns ea. ACS Chem Neurosci. 2021 Nov 3;12(21):4020-4036. doi: 10.1021/acschemneuro.1c00348. Epub 2021 Oct 22. ACS Chem Neurosci. 2021. PMID: 34676751
22 results