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Comparison of mutational profiles and clinical outcomes in patients with acute myeloid leukemia with mutated RUNX1 versus acute myeloid leukemia with myelodysplasia-related changes with mutated RUNX1.
Nguyen L, Zhang X, Roberts E, Yun S, McGraw K, Abraham I, Song J, Braswell D, Qin D, Sallman DA, Lancet JE, List AF, Moscinski LC, Padron E, Zhang L. Nguyen L, et al. Among authors: zhang l, zhang x. Leuk Lymphoma. 2020 Jun;61(6):1395-1405. doi: 10.1080/10428194.2020.1723016. Epub 2020 Feb 24. Leuk Lymphoma. 2020. PMID: 32091281 Free PMC article.
Defining Acute Myeloid Leukemia Ontogeny in Older Patients.
Melody M, Kuykendall A, Sallman D, Al Ali N, Zhang L, Talati C, Padron E, Sweet K, Extermann M, List A, Lancet J, Komrokji R. Melody M, et al. Among authors: zhang l. Clin Lymphoma Myeloma Leuk. 2020 May;20(5):312-315. doi: 10.1016/j.clml.2019.11.007. Epub 2019 Nov 9. Clin Lymphoma Myeloma Leuk. 2020. PMID: 32139296
MYC overexpression is associated with an early disease progression from MDS to AML.
Gajzer D, Logothetis CN, Sallman DA, Calon G, Babu A, Chan O, Vincelette ND, Volpe VO, Al Ali NH, Basra P, Talati C, Kuykendall AT, Mo Q, Padron E, Sweet K, Komrokji RS, Lancet JE, Yun S, Zhang L. Gajzer D, et al. Among authors: zhang l. Leuk Res. 2021 Dec;111:106733. doi: 10.1016/j.leukres.2021.106733. Epub 2021 Oct 21. Leuk Res. 2021. PMID: 34749168 Free PMC article.
Rosai-Dorfman Disease between Proliferation and Neoplasia.
Elbaz Younes I, Sokol L, Zhang L. Elbaz Younes I, et al. Among authors: zhang l. Cancers (Basel). 2022 Oct 27;14(21):5271. doi: 10.3390/cancers14215271. Cancers (Basel). 2022. PMID: 36358690 Free PMC article. Review.
Clinical Response to Upfront Targeted Tyrosine Kinase Inhibitors among Patients with Myeloid/Lymphoid Neoplasms with Eosinophilia and Tyrosine Kinase Gene Fusion.
Zhang Y, Nguyen L, Lu CM, Wang E, Lauw MIS, Ball S, Dong N, Moscinski L, Chan O, Yun S, Sallman D, Sokol L, Shah B, Knepper T, Lancet J, Komrokji R, Padron E, Kuykendall A, Zhang L. Zhang Y, et al. Among authors: zhang l. Clin Lymphoma Myeloma Leuk. 2023 Mar;23(3):e150-e163. doi: 10.1016/j.clml.2022.12.008. Epub 2022 Dec 18. Clin Lymphoma Myeloma Leuk. 2023. PMID: 36624015
Mutations highly specific for secondary AML are associated with poor outcomes in ELN favorable risk NPM1-mutated AML.
Chan O, Al Ali N, Tashkandi H, Ellis A, Ball S, Grenet J, Hana C, Deutsch Y, Zhang L, Hussaini M, Song J, Yun S, Talati C, Kuykendall A, Padron E, Walker A, Roboz G, Desai P, Sallman D, Sweet K, Komrokji R, Lancet J. Chan O, et al. Among authors: zhang l. Blood Adv. 2024 Mar 12;8(5):1075-1083. doi: 10.1182/bloodadvances.2023011173. Blood Adv. 2024. PMID: 38170740 Free PMC article.
SHP2 inhibition displays efficacy as a monotherapy and in combination with JAK2 inhibition in preclinical models of myeloproliferative neoplasms.
Pandey G, Mazzacurati L, Rowsell TM, Horvat NP, Amin NE, Zhang G, Akuffo AA, Colin-Leitzinger CM, Haura EB, Kuykendall AT, Zhang L, Epling-Burnette PK, Reuther GW. Pandey G, et al. Among authors: zhang l, zhang g. Am J Hematol. 2024 Jun;99(6):1040-1055. doi: 10.1002/ajh.27282. Epub 2024 Mar 5. Am J Hematol. 2024. PMID: 38440831
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