Su LL - Search Results

1

Structure of the interleukin-5 receptor complex exemplifies the organizing principle of common beta cytokine signaling.

Caveney NA, Rodriguez GE, Pollmann C, Meyer T, Borowska MT, Wilson SC, Wang N, Xiang X, Householder KD, Tao P, Su LL, Saxton RA, Piehler J, Garcia KC. Caveney NA, et al. Among authors: su ll. Mol Cell. 2024 May 16;84(10):1995-2005.e7. doi: 10.1016/j.molcel.2024.03.023. Epub 2024 Apr 12. Mol Cell. 2024. PMID: 38614096 Free article.

2

A structural blueprint for interleukin-21 signal modulation.

Abhiraman GC, Bruun TUJ, Caveney NA, Su LL, Saxton RA, Yin Q, Tang S, Davis MM, Jude KM, Garcia KC. Abhiraman GC, et al. Among authors: su ll. Cell Rep. 2023 Jun 27;42(6):112657. doi: 10.1016/j.celrep.2023.112657. Epub 2023 Jun 19. Cell Rep. 2023. PMID: 37339051 Free PMC article.

3

Structure-based decoupling of the pro- and anti-inflammatory functions of interleukin-10.

Saxton RA, Tsutsumi N, Su LL, Abhiraman GC, Mohan K, Henneberg LT, Aduri NG, Gati C, Garcia KC. Saxton RA, et al. Among authors: su ll. Science. 2021 Mar 19;371(6535):eabc8433. doi: 10.1126/science.abc8433. Science. 2021. PMID: 33737461 Free PMC article.

4

The tissue protective functions of interleukin-22 can be decoupled from pro-inflammatory actions through structure-based design.

Saxton RA, Henneberg LT, Calafiore M, Su L, Jude KM, Hanash AM, Garcia KC. Saxton RA, et al. Immunity. 2021 Apr 13;54(4):660-672.e9. doi: 10.1016/j.immuni.2021.03.008. Immunity. 2021. PMID: 33852830 Free PMC article.

5

Structure of the IFNγ receptor complex guides design of biased agonists.

Mendoza JL, Escalante NK, Jude KM, Sotolongo Bellon J, Su L, Horton TM, Tsutsumi N, Berardinelli SJ, Haltiwanger RS, Piehler J, Engleman EG, Garcia KC. Mendoza JL, et al. Nature. 2019 Mar;567(7746):56-60. doi: 10.1038/s41586-019-0988-7. Epub 2019 Feb 27. Nature. 2019. PMID: 30814731 Free PMC article.

6

Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells.

Glassman CR, Mathiharan YK, Jude KM, Su L, Panova O, Lupardus PJ, Spangler JB, Ely LK, Thomas C, Skiniotis G, Garcia KC. Glassman CR, et al. Cell. 2021 Feb 18;184(4):983-999.e24. doi: 10.1016/j.cell.2021.01.018. Cell. 2021. PMID: 33606986 Free PMC article.

7

Facile discovery of surrogate cytokine agonists.

Yen M, Ren J, Liu Q, Glassman CR, Sheahan TP, Picton LK, Moreira FR, Rustagi A, Jude KM, Zhao X, Blish CA, Baric RS, Su LL, Garcia KC. Yen M, et al. Among authors: su ll. Cell. 2022 Apr 14;185(8):1414-1430.e19. doi: 10.1016/j.cell.2022.02.025. Epub 2022 Mar 23. Cell. 2022. PMID: 35325595 Free PMC article.

8

Facile repurposing of peptide-MHC-restricted antibodies for cancer immunotherapy.

Yang X, Nishimiya D, Löchte S, Jude KM, Borowska M, Savvides CS, Dougan M, Su L, Zhao X, Piehler J, Garcia KC. Yang X, et al. Nat Biotechnol. 2023 Jul;41(7):932-943. doi: 10.1038/s41587-022-01567-w. Epub 2023 Jan 2. Nat Biotechnol. 2023. PMID: 36593402 Free PMC article.

9

Interleukin-2 superkines by computational design.

Ren J, Chu AE, Jude KM, Picton LK, Kare AJ, Su L, Montano Romero A, Huang PS, Garcia KC. Ren J, et al. Proc Natl Acad Sci U S A. 2022 Mar 22;119(12):e2117401119. doi: 10.1073/pnas.2117401119. Epub 2022 Mar 16. Proc Natl Acad Sci U S A. 2022. PMID: 35294290 Free PMC article.

10

Induced CD45 Proximity Potentiates Natural Killer Cell Receptor Antagonism.

Ren J, Jo Y, Picton LK, Su LL, Raulet DH, Garcia KC. Ren J, et al. Among authors: su ll. ACS Synth Biol. 2022 Oct 21;11(10):3426-3439. doi: 10.1021/acssynbio.2c00337. Epub 2022 Sep 28. ACS Synth Biol. 2022. PMID: 36169352 Free PMC article.

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