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Gene editing to prevent ventricular arrhythmias associated with cardiomyocyte cell therapy.
Marchiano S, Nakamura K, Reinecke H, Neidig L, Lai M, Kadota S, Perbellini F, Yang X, Klaiman JM, Blakely LP, Karbassi E, Fields PA, Fenix AM, Beussman KM, Jayabalu A, Kalucki FA, Potter JC, Futakuchi-Tsuchida A, Weber GJ, Dupras S, Tsuchida H, Pabon L, Wang L, Knollmann BC, Kattman S, Thies RS, Sniadecki N, MacLellan WR, Bertero A, Murry CE. Marchiano S, et al. Among authors: fenix am. Cell Stem Cell. 2023 May 4;30(5):741. doi: 10.1016/j.stem.2023.04.010. Cell Stem Cell. 2023. PMID: 37146587 Free PMC article. No abstract available.
Gene editing to prevent ventricular arrhythmias associated with cardiomyocyte cell therapy.
Marchiano S, Nakamura K, Reinecke H, Neidig L, Lai M, Kadota S, Perbellini F, Yang X, Klaiman JM, Blakely LP, Karbassi E, Fields PA, Fenix AM, Beussman KM, Jayabalu A, Kalucki FA, Potter JC, Futakuchi-Tsuchida A, Weber GJ, Dupras S, Tsuchida H, Pabon L, Wang L, Knollmann BC, Kattman S, Thies RS, Sniadecki N, MacLellan WR, Bertero A, Murry CE. Marchiano S, et al. Among authors: fenix am. Cell Stem Cell. 2023 Apr 6;30(4):396-414.e9. doi: 10.1016/j.stem.2023.03.010. Cell Stem Cell. 2023. PMID: 37028405 Free PMC article.
CRaTER enrichment for on-target gene editing enables generation of variant libraries in hiPSCs.
Friedman CE, Fayer S, Pendyala S, Chien WM, Loiben A, Tran L, Chao LS, Mckinstry A, Ahmed D, Karbassi E, Fenix AM, Murry CE, Starita LM, Fowler DM, Yang KC. Friedman CE, et al. Among authors: fenix am. J Mol Cell Cardiol. 2023 Jun;179:60-71. doi: 10.1016/j.yjmcc.2023.03.017. Epub 2023 Apr 3. J Mol Cell Cardiol. 2023. PMID: 37019277 Free article.
Independent regulation of Z-lines and M-lines during sarcomere assembly in cardiac myocytes revealed by the automatic image analysis software sarcApp.
Neininger-Castro AC, Hayes JB Jr, Sanchez ZC, Taneja N, Fenix AM, Moparthi S, Vassilopoulos S, Burnette DT. Neininger-Castro AC, et al. Among authors: fenix am. bioRxiv [Preprint]. 2023 Oct 6:2023.01.11.523681. doi: 10.1101/2023.01.11.523681. bioRxiv. 2023. PMID: 36711995 Free PMC article. Updated. Preprint.
Gain-of-function cardiomyopathic mutations in RBM20 rewire splicing regulation and re-distribute ribonucleoprotein granules within processing bodies.
Fenix AM, Miyaoka Y, Bertero A, Blue SM, Spindler MJ, Tan KKB, Perez-Bermejo JA, Chan AH, Mayerl SJ, Nguyen TD, Russell CR, Lizarraga PP, Truong A, So PL, Kulkarni A, Chetal K, Sathe S, Sniadecki NJ, Yeo GW, Murry CE, Conklin BR, Salomonis N. Fenix AM, et al. Nat Commun. 2021 Nov 3;12(1):6324. doi: 10.1038/s41467-021-26623-y. Nat Commun. 2021. PMID: 34732726 Free PMC article.
22 results