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Inhibition of the galactosyltransferase C1GALT1 reduces osteosarcoma cell proliferation by interfering with ERK signaling and cell cycle progression.
Watanabe K, Tasaka K, Ogata H, Kato S, Ueno H, Umeda K, Isobe T, Kubota Y, Sekiguchi M, Kimura S, Sato-Otsubo A, Hiwatari M, Ushiku T, Kato M, Oka A, Miyano S, Ogawa S, Takita J. Watanabe K, et al. Among authors: hiwatari m. Cancer Gene Ther. 2024 Apr 15. doi: 10.1038/s41417-024-00773-9. Online ahead of print. Cancer Gene Ther. 2024. PMID: 38622340
Integrated multiomics analysis of hepatoblastoma unravels its heterogeneity and provides novel druggable targets.
Sekiguchi M, Seki M, Kawai T, Yoshida K, Yoshida M, Isobe T, Hoshino N, Shirai R, Tanaka M, Souzaki R, Watanabe K, Arakawa Y, Nannya Y, Suzuki H, Fujii Y, Kataoka K, Shiraishi Y, Chiba K, Tanaka H, Shimamura T, Sato Y, Sato-Otsubo A, Kimura S, Kubota Y, Hiwatari M, Koh K, Hayashi Y, Kanamori Y, Kasahara M, Kohashi K, Kato M, Yoshioka T, Matsumoto K, Oka A, Taguchi T, Sanada M, Tanaka Y, Miyano S, Hata K, Ogawa S, Takita J. Sekiguchi M, et al. Among authors: hiwatari m. NPJ Precis Oncol. 2020 Jul 7;4:20. doi: 10.1038/s41698-020-0125-y. eCollection 2020. NPJ Precis Oncol. 2020. PMID: 32656360 Free PMC article.
Alteration of the immune environment in bone marrow from children with recurrent B cell precursor acute lymphoblastic leukemia.
Mikami T, Kato I, Wing JB, Ueno H, Tasaka K, Tanaka K, Kubota H, Saida S, Umeda K, Hiramatsu H, Isobe T, Hiwatari M, Okada A, Chiba K, Shiraishi Y, Tanaka H, Miyano S, Arakawa Y, Oshima K, Koh K, Adachi S, Iwaisako K, Ogawa S, Sakaguchi S, Takita J. Mikami T, et al. Among authors: hiwatari m. Cancer Sci. 2022 Jan;113(1):41-52. doi: 10.1111/cas.15186. Epub 2021 Nov 29. Cancer Sci. 2022. PMID: 34716967 Free PMC article.
Comprehensive genetic analysis of pediatric germ cell tumors identifies potential drug targets.
Kubota Y, Seki M, Kawai T, Isobe T, Yoshida M, Sekiguchi M, Kimura S, Watanabe K, Sato-Otsubo A, Yoshida K, Suzuki H, Kataoka K, Fujii Y, Shiraishi Y, Chiba K, Tanaka H, Hiwatari M, Oka A, Hayashi Y, Miyano S, Ogawa S, Hata K, Tanaka Y, Takita J. Kubota Y, et al. Among authors: hiwatari m. Commun Biol. 2020 Sep 30;3(1):544. doi: 10.1038/s42003-020-01267-8. Commun Biol. 2020. PMID: 32999426 Free PMC article.
A case of malignant rhabdoid tumor mimicking yolk sac tumor.
Kubota Y, Arakawa Y, Sekiguchi M, Watanabe K, Hiwatari M, Kishimoto H, Nakazawa A, Yoshida A, Ogawa S, Hanada R, Oka A, Takita J, Koh K. Kubota Y, et al. Among authors: hiwatari m. Pediatr Blood Cancer. 2019 Aug;66(8):e27784. doi: 10.1002/pbc.27784. Epub 2019 Apr 29. Pediatr Blood Cancer. 2019. PMID: 31034722
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