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Urolithin-A Promotes CD8+ T Cell-mediated Cancer Immunosurveillance via FOXO1 Activation.
Cancer Res Commun. 2024 May 3;4(5):1189-1198. doi: 10.1158/2767-9764.CRC-24-0022.
Cancer Res Commun. 2024.
PMID: 38626334
Free PMC article.
TGFβ limits Myc-dependent TCR-induced metabolic reprogramming in CD8+ T cells.
Hope HC, Pickersgill G, Ginefra P, Vannini N, Cook GP, Salmond RJ.
Hope HC, et al.
Front Immunol. 2022 Jul 26;13:913184. doi: 10.3389/fimmu.2022.913184. eCollection 2022.
Front Immunol. 2022.
PMID: 35958566
Free PMC article.
Item in Clipboard
Induction of mitochondrial recycling reverts age-associated decline of the hematopoietic and immune systems.
Girotra M, Chiang YH, Charmoy M, Ginefra P, Hope HC, Bataclan C, Yu YR, Schyrr F, Franco F, Geiger H, Cherix S, Ho PC, Naveiras O, Auwerx J, Held W, Vannini N.
Girotra M, et al. Among authors: hope hc.
Nat Aging. 2023 Sep;3(9):1057-1066. doi: 10.1038/s43587-023-00473-3. Epub 2023 Aug 31.
Nat Aging. 2023.
PMID: 37653255
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PGE2 inhibits TIL expansion by disrupting IL-2 signalling and mitochondrial function.
Morotti M, Grimm AJ, Hope HC, Arnaud M, Desbuisson M, Rayroux N, Barras D, Masid M, Murgues B, Chap BS, Ongaro M, Rota IA, Ronet C, Minasyan A, Chiffelle J, Lacher SB, Bobisse S, Murgues C, Ghisoni E, Ouchen K, Bou Mjahed R, Benedetti F, Abdellaoui N, Turrini R, Gannon PO, Zaman K, Mathevet P, Lelievre L, Crespo I, Conrad M, Verdeil G, Kandalaft LE, Dagher J, Corria-Osorio J, Doucey MA, Ho PC, Harari A, Vannini N, Böttcher JP, Dangaj Laniti D, Coukos G.
Morotti M, et al. Among authors: hope hc.
Nature. 2024 May;629(8011):426-434. doi: 10.1038/s41586-024-07352-w. Epub 2024 Apr 24.
Nature. 2024.
PMID: 38658764
Free PMC article.
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The Role of Non-essential Amino Acids in T Cell Function and Anti-tumour Immunity.
Hope HC, Salmond RJ.
Hope HC, et al.
Arch Immunol Ther Exp (Warsz). 2021 Oct 12;69(1):29. doi: 10.1007/s00005-021-00633-6.
Arch Immunol Ther Exp (Warsz). 2021.
PMID: 34637000
Free PMC article.
Review.
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Coordination of asparagine uptake and asparagine synthetase expression modulates CD8+ T cell activation.
Hope HC, Brownlie RJ, Fife CM, Steele L, Lorger M, Salmond RJ.
Hope HC, et al.
JCI Insight. 2021 May 10;6(9):e137761. doi: 10.1172/jci.insight.137761.
JCI Insight. 2021.
PMID: 33822775
Free PMC article.
Item in Clipboard
Targeting the tumor microenvironment and T cell metabolism for effective cancer immunotherapy.
Hope HC, Salmond RJ.
Hope HC, et al.
Eur J Immunol. 2019 Aug;49(8):1147-1152. doi: 10.1002/eji.201848058. Epub 2019 Jul 9.
Eur J Immunol. 2019.
PMID: 31270810
Free article.
Review.
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