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Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology.
Phan HV, Tsitsiklis A, Maguire CP, Haddad EK, Becker PM, Kim-Schulze S, Lee B, Chen J, Hoch A, Pickering H, van Zalm P, Altman MC, Augustine AD, Calfee CS, Bosinger S, Cairns CB, Eckalbar W, Guan L, Jayavelu ND, Kleinstein SH, Krammer F, Maecker HT, Ozonoff A, Peters B, Rouphael N; IMPACC Network; Montgomery RR, Reed E, Schaenman J, Steen H, Levy O, Diray-Arce J, Langelier CR. Phan HV, et al. Among authors: langelier cr. Sci Transl Med. 2024 Apr 17;16(743):eadj5154. doi: 10.1126/scitranslmed.adj5154. Epub 2024 Apr 17. Sci Transl Med. 2024. PMID: 38630846
Structural basis for ESCRT-III protein autoinhibition.
Bajorek M, Schubert HL, McCullough J, Langelier C, Eckert DM, Stubblefield WM, Uter NT, Myszka DG, Hill CP, Sundquist WI. Bajorek M, et al. Nat Struct Mol Biol. 2009 Jul;16(7):754-62. doi: 10.1038/nsmb.1621. Epub 2009 Jun 14. Nat Struct Mol Biol. 2009. PMID: 19525971 Free PMC article.
IFN-stimulated Gene Expression, Type 2 Inflammation, and Endoplasmic Reticulum Stress in Asthma.
Bhakta NR, Christenson SA, Nerella S, Solberg OD, Nguyen CP, Choy DF, Jung KL, Garudadri S, Bonser LR, Pollack JL, Zlock LT, Erle DJ, Langelier C, Derisi JL, Arron JR, Fahy JV, Woodruff PG. Bhakta NR, et al. Am J Respir Crit Care Med. 2018 Feb 1;197(3):313-324. doi: 10.1164/rccm.201706-1070OC. Am J Respir Crit Care Med. 2018. PMID: 29064281 Free PMC article.
Integrating host response and unbiased microbe detection for lower respiratory tract infection diagnosis in critically ill adults.
Langelier C, Kalantar KL, Moazed F, Wilson MR, Crawford ED, Deiss T, Belzer A, Bolourchi S, Caldera S, Fung M, Jauregui A, Malcolm K, Lyden A, Khan L, Vessel K, Quan J, Zinter M, Chiu CY, Chow ED, Wilson J, Miller S, Matthay MA, Pollard KS, Christenson S, Calfee CS, DeRisi JL. Langelier C, et al. Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):E12353-E12362. doi: 10.1073/pnas.1809700115. Epub 2018 Nov 27. Proc Natl Acad Sci U S A. 2018. PMID: 30482864 Free PMC article.
Metagenomic comparison of tracheal aspirate and mini-bronchial alveolar lavage for assessment of respiratory microbiota.
Kalantar KL, Moazed F, Christenson SC, Wilson J, Deiss T, Belzer A, Vessel K, Caldera S, Jauregui A, Bolourchi S, DeRisi JL, Calfee CS, Langelier C. Kalantar KL, et al. Am J Physiol Lung Cell Mol Physiol. 2019 Mar 1;316(3):L578-L584. doi: 10.1152/ajplung.00476.2018. Epub 2019 Jan 17. Am J Physiol Lung Cell Mol Physiol. 2019. PMID: 30652494 Free PMC article.
Upper airway gene expression differentiates COVID-19 from other acute respiratory illnesses and reveals suppression of innate immune responses by SARS-CoV-2.
Mick E, Kamm J, Pisco AO, Ratnasiri K, Babik JM, Calfee CS, Castañeda G, DeRisi JL, Detweiler AM, Hao S, Kangelaris KN, Kumar GR, Li LM, Mann SA, Neff N, Prasad PA, Serpa PH, Shah SJ, Spottiswoode N, Tan M, Christenson SA, Kistler A, Langelier C. Mick E, et al. medRxiv [Preprint]. 2020 May 19:2020.05.18.20105171. doi: 10.1101/2020.05.18.20105171. medRxiv. 2020. PMID: 32511476 Free PMC article. Updated. Preprint.
Dose-Dependent Pulmonary Toxicity of Aerosolized Vitamin E Acetate.
Matsumoto S, Fang X, Traber MG, Jones KD, Langelier C, Hayakawa Serpa P, Calfee CS, Matthay MA, Gotts JE. Matsumoto S, et al. Am J Respir Cell Mol Biol. 2020 Dec;63(6):748-757. doi: 10.1165/rcmb.2020-0209OC. Am J Respir Cell Mol Biol. 2020. PMID: 32822237 Free PMC article.
Global Absence and Targeting of Protective Immune States in Severe COVID-19.
Combes AJ, Courau T, Kuhn NF, Hu KH, Ray A, Chen WS, Cleary SJ, Chew NW, Kushnoor D, Reeder GC, Shen A, Tsui J, Hiam-Galvez KJ, Muñoz-Sandoval P, Zhu WS, Lee DS, Sun Y, You R, Magnen M, Rodriguez L, Leligdowicz A, Zamecnik CR, Loudermilk RP, Wilson MR, Ye CJ, Fragiadakis GK, Looney MR, Chan V, Ward A, Carrillo S; UCSF COMET Consortium; Matthay M, Erle DJ, Woodruff PG, Langelier C, Kangelaris K, Hendrickson CM, Calfee C, Rao AA, Krummel MF. Combes AJ, et al. Among authors: langelier c. Res Sq [Preprint]. 2020 Oct 28:rs.3.rs-97042. doi: 10.21203/rs.3.rs-97042/v1. Res Sq. 2020. PMID: 33140041 Free PMC article. Updated. Preprint.
117 results