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Comparison of tau spread in people with Down syndrome versus autosomal-dominant Alzheimer's disease: a cross-sectional study.
Wisch JK, McKay NS, Boerwinkle AH, Kennedy J, Flores S, Handen BL, Christian BT, Head E, Mapstone M, Rafii MS, O'Bryant SE, Price JC, Laymon CM, Krinsky-McHale SJ, Lai F, Rosas HD, Hartley SL, Zaman S, Lott IT, Tudorascu D, Zammit M, Brickman AM, Lee JH, Bird TD, Cohen A, Chrem P, Daniels A, Chhatwal JP, Cruchaga C, Ibanez L, Jucker M, Karch CM, Day GS, Lee JH, Levin J, Llibre-Guerra J, Li Y, Lopera F, Roh JH, Ringman JM, Supnet-Bell C, van Dyck CH, Xiong C, Wang G, Morris JC, McDade E, Bateman RJ, Benzinger TLS, Gordon BA, Ances BM; Alzheimer's Biomarker Consortium-Down syndrome; Dominantly Inherited Alzheimer Network. Wisch JK, et al. Among authors: christian bt. Lancet Neurol. 2024 May;23(5):500-510. doi: 10.1016/S1474-4422(24)00084-X. Lancet Neurol. 2024. PMID: 38631766
Alzheimer-Like Pattern of Hypometabolism Emerges with Elevated Amyloid-β Burden in Down Syndrome.
Lao PJ, Handen BL, Betthauser TJ, Mihaila I, Hartley SL, Cohen AD, Tudorascu DL, Bulova PD, Lopresti BJ, Tumuluru RV, Murali D, Mathis CA, Barnhart TE, Stone CK, Price JC, Devenny DA, Johnson SC, Klunk WE, Christian BT. Lao PJ, et al. Among authors: christian bt. J Alzheimers Dis. 2018;61(2):631-644. doi: 10.3233/JAD-170720. J Alzheimers Dis. 2018. PMID: 29254096 Free PMC article.
Neuropathological correlates of amyloid PET imaging in Down syndrome.
Abrahamson EE, Head E, Lott IT, Handen BL, Mufson EJ, Christian BT, Klunk WE, Ikonomovic MD. Abrahamson EE, et al. Among authors: christian bt. Dev Neurobiol. 2019 Jul;79(7):750-766. doi: 10.1002/dneu.22713. Epub 2019 Aug 17. Dev Neurobiol. 2019. PMID: 31379087 Free PMC article. Review.
PET measurement of longitudinal amyloid load identifies the earliest stages of amyloid-beta accumulation during Alzheimer's disease progression in Down syndrome.
Zammit MD, Tudorascu DL, Laymon CM, Hartley SL, Zaman SH, Ances BM, Johnson SC, Stone CK, Mathis CA, Klunk WE, Cohen AD, Handen BL, Christian BT. Zammit MD, et al. Among authors: christian bt. Neuroimage. 2021 Mar;228:117728. doi: 10.1016/j.neuroimage.2021.117728. Epub 2021 Jan 7. Neuroimage. 2021. PMID: 33421595 Free PMC article.
Neurofibrillary tau depositions emerge with subthreshold cerebral beta-amyloidosis in down syndrome.
Zammit MD, Tudorascu DL, Laymon CM, Hartley SL, Ellison PA, Zaman SH, Ances BM, Johnson SC, Stone CK, Sabbagh MN, Mathis CA, Klunk WE, Cohen AD, Handen BL, Christian BT. Zammit MD, et al. Among authors: christian bt. Neuroimage Clin. 2021;31:102740. doi: 10.1016/j.nicl.2021.102740. Epub 2021 Jun 24. Neuroimage Clin. 2021. PMID: 34182407 Free PMC article.
195 results