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Antibodies targeting the shared cytokine receptor IL-1 receptor accessory protein invoke distinct mechanisms to block all cytokine signaling.
Cell Rep. 2024 Apr 11:114099. doi: 10.1016/j.celrep.2024.114099. Online ahead of print.
Cell Rep. 2024.
PMID: 38636519
Free article.
Molecular Basis of Selective Cytokine Signaling Inhibition by Antibodies Targeting a Shared Receptor.
Fields JK, Kihn K, Birkedal GS, Klontz EH, Sjöström K, Günther S, Beadenkopf R, Forsberg G, Liberg D, Snyder GA, Deredge D, Sundberg EJ.
Fields JK, et al. Among authors: birkedal gs.
Front Immunol. 2021 Dec 24;12:779100. doi: 10.3389/fimmu.2021.779100. eCollection 2021.
Front Immunol. 2021.
PMID: 35003094
Free PMC article.
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