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A panel of recombinant Leishmania donovani cell surface and secreted proteins identifies LdBPK_323600.1 as a serological marker of symptomatic infection.
Roberts AJ, Ong HB, Clare S, Brandt C, Harcourt K, Takele Y, Ghosh P, Toepp A, Waugh M, Matano D, Färnert A, Adams E, Moreno J, Mbuchi M, Petersen C, Mondal D, Kropf P, Wright GJ. Roberts AJ, et al. Among authors: harcourt k. mBio. 2024 May 8;15(5):e0085924. doi: 10.1128/mbio.00859-24. Epub 2024 Apr 19. mBio. 2024. PMID: 38639536 Free PMC article.
Systematic identification of genes encoding cell surface and secreted proteins that are essential for in vitro growth and infection in Leishmania donovani.
Roberts AJ, Ong HB, Clare S, Brandt C, Harcourt K, Franssen SU, Cotton JA, Müller-Sienerth N, Wright GJ. Roberts AJ, et al. Among authors: harcourt k. PLoS Pathog. 2022 Feb 24;18(2):e1010364. doi: 10.1371/journal.ppat.1010364. eCollection 2022 Feb. PLoS Pathog. 2022. PMID: 35202447 Free PMC article.
An invariant Trypanosoma vivax vaccine antigen induces protective immunity.
Autheman D, Crosnier C, Clare S, Goulding DA, Brandt C, Harcourt K, Tolley C, Galaway F, Khushu M, Ong H, Romero-Ramirez A, Duffy CW, Jackson AP, Wright GJ. Autheman D, et al. Among authors: harcourt k. Nature. 2021 Jul;595(7865):96-100. doi: 10.1038/s41586-021-03597-x. Epub 2021 May 26. Nature. 2021. PMID: 34040257
Vivaxin genes encode highly immunogenic, non-variant antigens on the Trypanosoma vivax cell-surface.
Romero-Ramirez A, Casas-Sánchez A, Autheman D, Duffy CW, Brandt C, Clare S, Harcourt K, André MR, de Almeida Castilho Neto KJG, Teixeira MMG, Machado RZ, Coombes J, Flynn RJ, Wright GJ, Jackson AP. Romero-Ramirez A, et al. Among authors: harcourt k. PLoS Negl Trop Dis. 2022 Sep 21;16(9):e0010791. doi: 10.1371/journal.pntd.0010791. eCollection 2022 Sep. PLoS Negl Trop Dis. 2022. PMID: 36129968 Free PMC article.
Reliable, scalable functional genetics in bloodstream-form Trypanosoma congolense in vitro and in vivo.
Awuah-Mensah G, McDonald J, Steketee PC, Autheman D, Whipple S, D'Archivio S, Brandt C, Clare S, Harcourt K, Wright GJ, Morrison LJ, Gadelha C, Wickstead B. Awuah-Mensah G, et al. Among authors: harcourt k. PLoS Pathog. 2021 Jan 22;17(1):e1009224. doi: 10.1371/journal.ppat.1009224. eCollection 2021 Jan. PLoS Pathog. 2021. PMID: 33481935 Free PMC article.
Interferon lambda is required for interferon gamma-expressing NK cell responses but does not afford antiviral protection during acute and persistent murine cytomegalovirus infection.
Gimeno Brias S, Marsden M, Forbester J, Clement M, Brandt C, Harcourt K, Kane L, Chapman L, Clare S, Humphreys IR. Gimeno Brias S, et al. Among authors: harcourt k. PLoS One. 2018 May 16;13(5):e0197596. doi: 10.1371/journal.pone.0197596. eCollection 2018. PLoS One. 2018. PMID: 29768502 Free PMC article.
New Variant of Multidrug-Resistant Salmonella enterica Serovar Typhimurium Associated with Invasive Disease in Immunocompromised Patients in Vietnam.
Mather AE, Phuong TLT, Gao Y, Clare S, Mukhopadhyay S, Goulding DA, Hoang NTD, Tuyen HT, Lan NPH, Thompson CN, Trang NHT, Carrique-Mas J, Tue NT, Campbell JI, Rabaa MA, Thanh DP, Harcourt K, Hoa NT, Trung NV, Schultsz C, Perron GG, Coia JE, Brown DJ, Okoro C, Parkhill J, Thomson NR, Chau NVV, Thwaites GE, Maskell DJ, Dougan G, Kenney LJ, Baker S. Mather AE, et al. Among authors: harcourt k. mBio. 2018 Sep 4;9(5):e01056-18. doi: 10.1128/mBio.01056-18. mBio. 2018. PMID: 30181247 Free PMC article.
The gut microbial metabolic capacity of microbiome-humanized vs. wild type rodents reveals a likely dual role of intestinal bacteria in hepato-intestinal schistosomiasis.
Cortés A, Martin J, Rosa BA, Stark KA, Clare S, McCarthy C, Harcourt K, Brandt C, Tolley C, Lawley TD, Mitreva M, Berriman M, Rinaldi G, Cantacessi C. Cortés A, et al. Among authors: harcourt k. PLoS Negl Trop Dis. 2022 Oct 24;16(10):e0010878. doi: 10.1371/journal.pntd.0010878. eCollection 2022 Oct. PLoS Negl Trop Dis. 2022. PMID: 36279280 Free PMC article.
59 results