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Cross-platform proteomics signatures of extreme old age.
Reed ER, Chandler KB, Lopez P, Costello CE, Andersen SL, Perls TT, Li M, Bae H, Soerensen M, Monti S, Sebastiani P. Reed ER, et al. Among authors: perls tt. bioRxiv [Preprint]. 2024 Apr 14:2024.04.10.588876. doi: 10.1101/2024.04.10.588876. bioRxiv. 2024. PMID: 38645061 Free PMC article. Preprint.
Whole genome-wide sequence analysis of long-lived families (Long-Life Family Study) identifies MTUS2 gene associated with late-onset Alzheimer's disease.
Xicota L, Cosentino S, Vardarajan B, Mayeux R, Perls TT, Andersen SL, Zmuda JM, Thyagarajan B, Yashin A, Wojczynski MK, Krinsky-McHale S, Handen BL, Christian BT, Head E, Mapstone ME, Schupf N, Lee JH, Barral S; Long‐Life Family Study (LLFS); Alzheimer's Disease Genetic Consortium (ADGC); Alzheimer's Biomarkers Consortium‐Down Syndrome (ABC‐DS). Xicota L, et al. Among authors: perls tt. Alzheimers Dement. 2024 Apr;20(4):2670-2679. doi: 10.1002/alz.13718. Epub 2024 Feb 21. Alzheimers Dement. 2024. PMID: 38380866 Free PMC article.
Multi-modal profiling of peripheral blood cells across the human lifespan reveals distinct immune cell signatures of aging and longevity.
Karagiannis TT, Dowrey TW, Villacorta-Martin C, Montano M, Reed E, Belkina AC, Andersen SL, Perls TT, Monti S, Murphy GJ, Sebastiani P. Karagiannis TT, et al. Among authors: perls tt. EBioMedicine. 2023 Apr;90:104514. doi: 10.1016/j.ebiom.2023.104514. Epub 2023 Mar 31. EBioMedicine. 2023. PMID: 37005201 Free PMC article.
Mosaic Chromosomal Alterations and Human Longevity.
Leshchyk A, Xiang Q, Andersen SL, Gurinovich A, Song Z, Lee JH, Christensen K, Yashin A, Wojczynski M, Schwander K, Perls TT, Monti S, Sebastiani P. Leshchyk A, et al. Among authors: perls tt. J Gerontol A Biol Sci Med Sci. 2023 Aug 27;78(9):1561-1568. doi: 10.1093/gerona/glad095. J Gerontol A Biol Sci Med Sci. 2023. PMID: 36988570 Free PMC article.
A Genome-Wide Association Study of 2304 Extreme Longevity Cases Identifies Novel Longevity Variants.
Bae H, Gurinovich A, Karagiannis TT, Song Z, Leshchyk A, Li M, Andersen SL, Arbeev K, Yashin A, Zmuda J, An P, Feitosa M, Giuliani C, Franceschi C, Garagnani P, Mengel-From J, Atzmon G, Barzilai N, Puca A, Schork NJ, Perls TT, Sebastiani P. Bae H, et al. Among authors: perls tt. Int J Mol Sci. 2022 Dec 21;24(1):116. doi: 10.3390/ijms24010116. Int J Mol Sci. 2022. PMID: 36613555 Free PMC article.
A metabolomic signature of the APOE2 allele.
Sebastiani P, Song Z, Ellis D, Tian Q, Schwaiger-Haber M, Stancliffe E, Lustgarten MS, Funk CC, Baloni P, Yao CH, Joshi S, Marron MM, Gurinovich A, Li M, Leshchyk A, Xiang Q, Andersen SL, Feitosa MF, Ukraintseva S, Soerensen M, Fiehn O, Ordovas JM, Haigis M, Monti S, Barzilai N, Milman S, Ferrucci L, Rappaport N, Patti GJ, Perls TT. Sebastiani P, et al. Among authors: perls tt. Geroscience. 2023 Feb;45(1):415-426. doi: 10.1007/s11357-022-00646-9. Epub 2022 Aug 23. Geroscience. 2023. PMID: 35997888 Free PMC article.
121 results