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Multi-pronged analysis of pediatric low-grade glioma reveals a unique tumor microenvironment associated with BRAF alterations.
Zahedi S, Riemondy K, Griesinger AM, Donson AM, Fu R, Crespo M, DeSisto J, Groat MM, Bratbak E, Green A, Hankinson TC, Handler M, Vibhakar R, Willard N, Foreman NK, Levy JM. Zahedi S, et al. Among authors: desisto j. bioRxiv [Preprint]. 2024 Apr 10:2024.04.05.588294. doi: 10.1101/2024.04.05.588294. bioRxiv. 2024. PMID: 38645202 Free PMC article. Preprint.
Mapping pediatric brain tumors to their origins in the developing cerebellum.
Okonechnikov K, Joshi P, Sepp M, Leiss K, Sarropoulos I, Murat F, Sill M, Beck P, Chan KC, Korshunov A, Sah F, Deng MY, Sturm D, DeSisto J, Donson AM, Foreman NK, Green AL, Robinson G, Orr BA, Gao Q, Darrow E, Hadley JL, Northcott PA, Gojo J, Kawauchi D, Hovestadt V, Filbin MG, von Deimling A, Zuckermann M, Pajtler KW, Kool M, Jones DTW, Jäger N, Kutscher LM, Kaessmann H, Pfister SM. Okonechnikov K, et al. Among authors: desisto j. Neuro Oncol. 2023 Oct 3;25(10):1895-1909. doi: 10.1093/neuonc/noad124. Neuro Oncol. 2023. PMID: 37534924 Free PMC article.
Recurrent atypical teratoid/rhabdoid tumors (AT/RT) reveal discrete features of progression on histology, epigenetics, copy number profiling, and transcriptomics.
Johann PD, Altendorf L, Efremova EM, Holsten T, Steinbügl M, Nemes K, Eckhardt A, Kresbach C, Bockmayr M, Koch A, Haberler C, Antonelli M, DeSisto J, Schuhmann MU, Hauser P, Siebert R, Bens S, Kool M, Green AL, Hasselblatt M, Frühwald MC, Schüller U. Johann PD, et al. Among authors: desisto j. Acta Neuropathol. 2023 Sep;146(3):527-541. doi: 10.1007/s00401-023-02608-7. Epub 2023 Jul 14. Acta Neuropathol. 2023. PMID: 37450044 Free PMC article.
A novel preclinical model of craniospinal irradiation in pediatric diffuse midline glioma demonstrates decreased metastatic disease.
Knox AJ, Van Court B, Oweida A, Barsh E, DeSisto J, Flannery P, Lemma R, Chatwin H, Vibhakar R, Dorris K, Serkova NJ, Karam SD, Gilani A, Green AL. Knox AJ, et al. Among authors: desisto j. Front Oncol. 2023 Apr 12;13:1105395. doi: 10.3389/fonc.2023.1105395. eCollection 2023. Front Oncol. 2023. PMID: 37124531 Free PMC article.
Novel RAF Fusions in Pediatric Low-Grade Gliomas Demonstrate MAPK Pathway Activation.
Lind KT, Chatwin HV, DeSisto J, Coleman P, Sanford B, Donson AM, Davies KD, Willard N, Ewing CA, Knox AJ, Mulcahy Levy JM, Gilani A, Green AL. Lind KT, et al. Among authors: desisto j. J Neuropathol Exp Neurol. 2021 Dec 29;80(12):1099-1107. doi: 10.1093/jnen/nlab110. J Neuropathol Exp Neurol. 2021. PMID: 34850053
Comprehensive molecular characterization of pediatric radiation-induced high-grade glioma.
DeSisto J, Lucas JT Jr, Xu K, Donson A, Lin T, Sanford B, Wu G, Tran QT, Hedges D, Hsu CY, Armstrong GT, Arnold M, Bhatia S, Flannery P, Lemma R, Hardie L, Schüller U, Venkataraman S, Hoffman LM, Dorris K, Mulcahy Levy JM, Hankinson TC, Handler M, Liu AK, Foreman N, Vibhakar R, Jones K, Allen S, Zhang J, Baker SJ, Merchant TE, Orr BA, Green AL. DeSisto J, et al. Nat Commun. 2021 Sep 20;12(1):5531. doi: 10.1038/s41467-021-25709-x. Nat Commun. 2021. PMID: 34545084 Free PMC article.
Preclinical and clinical investigation of intratumoral chemotherapy pharmacokinetics in DIPG using gemcitabine.
Green AL, Flannery P, Hankinson TC, O'Neill B, Amani V, DeSisto J, Knox A, Chatwin H, Lemma R, Hoffman LM, Mulcahy Levy J, Raybin J, Hemenway M, Gilani A, Koschmann C, Dahl N, Handler M, Pierce A, Venkataraman S, Foreman N, Vibhakar R, Wempe MF, Dorris K. Green AL, et al. Among authors: desisto j. Neurooncol Adv. 2020 Feb 24;2(1):vdaa021. doi: 10.1093/noajnl/vdaa021. eCollection 2020 Jan-Dec. Neurooncol Adv. 2020. PMID: 32642682 Free PMC article.
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