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Multi-pronged analysis of pediatric low-grade glioma reveals a unique tumor microenvironment associated with BRAF alterations.
Zahedi S, Riemondy K, Griesinger AM, Donson AM, Fu R, Crespo M, DeSisto J, Groat MM, Bratbak E, Green A, Hankinson TC, Handler M, Vibhakar R, Willard N, Foreman NK, Levy JM. Zahedi S, et al. Among authors: donson am. bioRxiv [Preprint]. 2024 Apr 10:2024.04.05.588294. doi: 10.1101/2024.04.05.588294. bioRxiv. 2024. PMID: 38645202 Free PMC article. Preprint.
Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors.
Mulcahy Levy JM, Zahedi S, Griesinger AM, Morin A, Davies KD, Aisner DL, Kleinschmidt-DeMasters BK, Fitzwalter BE, Goodall ML, Thorburn J, Amani V, Donson AM, Birks DK, Mirsky DM, Hankinson TC, Handler MH, Green AL, Vibhakar R, Foreman NK, Thorburn A. Mulcahy Levy JM, et al. Among authors: donson am. Elife. 2017 Jan 17;6:e19671. doi: 10.7554/eLife.19671. Elife. 2017. PMID: 28094001 Free PMC article.
Targeted fusion analysis can aid in the classification and treatment of pediatric glioma, ependymoma, and glioneuronal tumors.
Lake JA, Donson AM, Prince E, Davies KD, Nellan A, Green AL, Mulcahy Levy J, Dorris K, Vibhakar R, Hankinson TC, Foreman NK, Ewalt MD, Kleinschmidt-DeMasters BK, Hoffman LM, Gilani A. Lake JA, et al. Among authors: donson am. Pediatr Blood Cancer. 2020 Jan;67(1):e28028. doi: 10.1002/pbc.28028. Epub 2019 Oct 8. Pediatr Blood Cancer. 2020. PMID: 31595628 Free PMC article.
Comprehensive molecular characterization of pediatric radiation-induced high-grade glioma.
DeSisto J, Lucas JT Jr, Xu K, Donson A, Lin T, Sanford B, Wu G, Tran QT, Hedges D, Hsu CY, Armstrong GT, Arnold M, Bhatia S, Flannery P, Lemma R, Hardie L, Schüller U, Venkataraman S, Hoffman LM, Dorris K, Mulcahy Levy JM, Hankinson TC, Handler M, Liu AK, Foreman N, Vibhakar R, Jones K, Allen S, Zhang J, Baker SJ, Merchant TE, Orr BA, Green AL. DeSisto J, et al. Nat Commun. 2021 Sep 20;12(1):5531. doi: 10.1038/s41467-021-25709-x. Nat Commun. 2021. PMID: 34545084 Free PMC article.
Multi-omic approach identifies hypoxic tumor-associated myeloid cells that drive immunobiology of high-risk pediatric ependymoma.
Griesinger AM, Riemondy K, Eswaran N, Donson AM, Willard N, Prince EW, Paine SML, Bowes G, Rheaume J, Chapman RJ, Ramage J, Jackson A, Grundy RG, Foreman NK, Ritzmann TA. Griesinger AM, et al. Among authors: donson am. iScience. 2023 Aug 9;26(9):107585. doi: 10.1016/j.isci.2023.107585. eCollection 2023 Sep 15. iScience. 2023. PMID: 37694144 Free PMC article.
Integration of single-nuclei RNA-sequencing, spatial transcriptomics and histochemistry defines the complex microenvironment of NF1-associated plexiform neurofibromas.
Amani V, Riemondy KA, Fu R, Griesinger AM, Grimaldo E, De Sousa GR, Gilani A, Hemenway M, Foreman NK, Donson AM, Willard N. Amani V, et al. Among authors: donson am. Acta Neuropathol Commun. 2023 Sep 28;11(1):158. doi: 10.1186/s40478-023-01639-1. Acta Neuropathol Commun. 2023. PMID: 37770931 Free PMC article.
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