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Multi-pronged analysis of pediatric low-grade glioma reveals a unique tumor microenvironment associated with BRAF alterations.
Zahedi S, Riemondy K, Griesinger AM, Donson AM, Fu R, Crespo M, DeSisto J, Groat MM, Bratbak E, Green A, Hankinson TC, Handler M, Vibhakar R, Willard N, Foreman NK, Levy JM. Zahedi S, et al. Among authors: griesinger am. bioRxiv [Preprint]. 2024 Apr 10:2024.04.05.588294. doi: 10.1101/2024.04.05.588294. bioRxiv. 2024. PMID: 38645202 Free PMC article. Preprint.
Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors.
Mulcahy Levy JM, Zahedi S, Griesinger AM, Morin A, Davies KD, Aisner DL, Kleinschmidt-DeMasters BK, Fitzwalter BE, Goodall ML, Thorburn J, Amani V, Donson AM, Birks DK, Mirsky DM, Hankinson TC, Handler MH, Green AL, Vibhakar R, Foreman NK, Thorburn A. Mulcahy Levy JM, et al. Among authors: griesinger am. Elife. 2017 Jan 17;6:e19671. doi: 10.7554/eLife.19671. Elife. 2017. PMID: 28094001 Free PMC article.
Multi-omic approach identifies hypoxic tumor-associated myeloid cells that drive immunobiology of high-risk pediatric ependymoma.
Griesinger AM, Riemondy K, Eswaran N, Donson AM, Willard N, Prince EW, Paine SML, Bowes G, Rheaume J, Chapman RJ, Ramage J, Jackson A, Grundy RG, Foreman NK, Ritzmann TA. Griesinger AM, et al. iScience. 2023 Aug 9;26(9):107585. doi: 10.1016/j.isci.2023.107585. eCollection 2023 Sep 15. iScience. 2023. PMID: 37694144 Free PMC article.
Integration of single-nuclei RNA-sequencing, spatial transcriptomics and histochemistry defines the complex microenvironment of NF1-associated plexiform neurofibromas.
Amani V, Riemondy KA, Fu R, Griesinger AM, Grimaldo E, De Sousa GR, Gilani A, Hemenway M, Foreman NK, Donson AM, Willard N. Amani V, et al. Among authors: griesinger am. Acta Neuropathol Commun. 2023 Sep 28;11(1):158. doi: 10.1186/s40478-023-01639-1. Acta Neuropathol Commun. 2023. PMID: 37770931 Free PMC article.
Single-Cell RNA Sequencing of Childhood Ependymoma Reveals Neoplastic Cell Subpopulations That Impact Molecular Classification and Etiology.
Gillen AE, Riemondy KA, Amani V, Griesinger AM, Gilani A, Venkataraman S, Madhavan K, Prince E, Sanford B, Hankinson TC, Handler MH, Vibhakar R, Jones KL, Mitra S, Hesselberth JR, Foreman NK, Donson AM. Gillen AE, et al. Among authors: griesinger am. Cell Rep. 2020 Aug 11;32(6):108023. doi: 10.1016/j.celrep.2020.108023. Cell Rep. 2020. PMID: 32783945 Free PMC article.
Neoplastic and immune single-cell transcriptomics define subgroup-specific intra-tumoral heterogeneity of childhood medulloblastoma.
Riemondy KA, Venkataraman S, Willard N, Nellan A, Sanford B, Griesinger AM, Amani V, Mitra S, Hankinson TC, Handler MH, Sill M, Ocasio J, Weir SJ, Malawsky DS, Gershon TR, Garancher A, Wechsler-Reya RJ, Hesselberth JR, Foreman NK, Donson AM, Vibhakar R. Riemondy KA, et al. Among authors: griesinger am. Neuro Oncol. 2022 Feb 1;24(2):273-286. doi: 10.1093/neuonc/noab135. Neuro Oncol. 2022. PMID: 34077540 Free PMC article.
31 results