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Page 1
Ergothioneine boosts mitochondrial respiration and exercise performance via direct activation of MPST.
Sprenger HG, Mittenbühler MJ, Sun Y, Van Vranken JG, Schindler S, Jayaraj A, Khetarpal SA, Vargas-Castillo A, Puszynska AM, Spinelli JB, Armani A, Kunchok T, Ryback B, Seo HS, Song K, Sebastian L, O'Young C, Braithwaite C, Dhe-Paganon S, Burger N, Mills EL, Gygi SP, Arthanari H, Chouchani ET, Sabatini DM, Spiegelman BM. Sprenger HG, et al. Among authors: van vranken jg. bioRxiv [Preprint]. 2024 Apr 10:2024.04.10.588849. doi: 10.1101/2024.04.10.588849. bioRxiv. 2024. PMID: 38645260 Free PMC article. Preprint.
Mustn1 is a smooth muscle cell-secreted microprotein that modulates skeletal muscle extracellular matrix composition.
Ducommun S, Jannig PR, Cervenka I, Murgia M, Mittenbühler MJ, Chernogubova E, Dias JM, Jude B, Correia JC, Van Vranken JG, Ocana-Santero G, Porsmyr-Palmertz M, McCann Haworth S, Martínez-Redondo V, Liu Z, Carlström M, Mann M, Lanner JT, Teixeira AI, Maegdefessel L, Spiegelman BM, Ruas JL. Ducommun S, et al. Among authors: van vranken jg. Mol Metab. 2024 Apr;82:101912. doi: 10.1016/j.molmet.2024.101912. Epub 2024 Mar 6. Mol Metab. 2024. PMID: 38458566 Free PMC article.
Phosphate starvation signaling increases mitochondrial membrane potential through respiration-independent mechanisms.
Ouyang Y, Jeong MY, Cunningham CN, Berg JA, Toshniwal AG, Hughes CE, Seiler K, Van Vranken JG, Cluntun AA, Lam G, Winter JM, Akdogan E, Dove KK, Nowinski SM, West M, Odorizzi G, Gygi SP, Dunn CD, Winge DR, Rutter J. Ouyang Y, et al. Among authors: van vranken jg. Elife. 2024 Jan 22;13:e84282. doi: 10.7554/eLife.84282. Elife. 2024. PMID: 38251707 Free PMC article.
Insulin sensitization by small molecules enhancing GLUT4 translocation.
Yin TC, Van Vranken JG, Srivastava D, Mittal A, Buscaglia P, Moore AE, Verdinez JA, Graham AE, Walsh SA, Acevedo MA, Kerns RJ, Artemyev NO, Gygi SP, Sebag JA. Yin TC, et al. Among authors: van vranken jg. Cell Chem Biol. 2023 Aug 17;30(8):933-942.e6. doi: 10.1016/j.chembiol.2023.06.012. Epub 2023 Jul 14. Cell Chem Biol. 2023. PMID: 37453421
Isolation of extracellular fluids reveals novel secreted bioactive proteins from muscle and fat tissues.
Mittenbühler MJ, Jedrychowski MP, Van Vranken JG, Sprenger HG, Wilensky S, Dumesic PA, Sun Y, Tartaglia A, Bogoslavski D, A M, Xiao H, Blackmore KA, Reddy A, Gygi SP, Chouchani ET, Spiegelman BM. Mittenbühler MJ, et al. Among authors: van vranken jg. Cell Metab. 2023 Mar 7;35(3):535-549.e7. doi: 10.1016/j.cmet.2022.12.014. Epub 2023 Jan 20. Cell Metab. 2023. PMID: 36681077 Free PMC article.
A proteome-wide atlas of drug mechanism of action.
Mitchell DC, Kuljanin M, Li J, Van Vranken JG, Bulloch N, Schweppe DK, Huttlin EL, Gygi SP. Mitchell DC, et al. Among authors: van vranken jg. Nat Biotechnol. 2023 Jun;41(6):845-857. doi: 10.1038/s41587-022-01539-0. Epub 2023 Jan 2. Nat Biotechnol. 2023. PMID: 36593396 Free PMC article.
Amelioration of pathologic α-synuclein-induced Parkinson's disease by irisin.
Kam TI, Park H, Chou SC, Van Vranken JG, Mittenbühler MJ, Kim H, A M, Choi YR, Biswas D, Wang J, Shin Y, Loder A, Karuppagounder SS, Wrann CD, Dawson VL, Spiegelman BM, Dawson TM. Kam TI, et al. Among authors: van vranken jg. Proc Natl Acad Sci U S A. 2022 Sep 6;119(36):e2204835119. doi: 10.1073/pnas.2204835119. Epub 2022 Aug 31. Proc Natl Acad Sci U S A. 2022. PMID: 36044549 Free PMC article.
22 results