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Anti-tumor activity of a novel LAIR1 antagonist in combination with anti-PD-1 to treat collagen-rich solid tumors.
Rodriguez BL, Huang J, Gibson L, Fradette JJ, Chen HH, Koyano K, Cortez C, Li B, Ho C, Ashique AM, Lin VY, Crawley S, Roda JM, Chen P, Fan B, Kim J, Sissons J, Sitrin J, Kaplan DD, Gibbons DL, Rivera LB. Rodriguez BL, et al. Among authors: chen hh, chen p. Mol Cancer Ther. 2024 Apr 22. doi: 10.1158/1535-7163.MCT-23-0866. Online ahead of print. Mol Cancer Ther. 2024. PMID: 38648067
The Fibronectin-ILT3 Interaction Functions as a Stromal Checkpoint that Suppresses Myeloid Cells.
Paavola KJ, Roda JM, Lin VY, Chen P, O'Hollaren KP, Ventura R, Crawley SC, Li B, Chen HH, Malmersjö S, Sharkov NA, Horner G, Guo W, Kutach AK, Mondal K, Zhang Z, Lichtman JS, Song C, Rivera LB, Liu W, Luo J, Wang Y, Solloway MJ, Allan BB, Kekatpure A, Starck SR, Haldankar R, Fan B, Chu C, Tang J, Molgora M, Colonna M, Kaplan DD, Hsu JY. Paavola KJ, et al. Among authors: chen hh, chen p. Cancer Immunol Res. 2021 Nov;9(11):1283-1297. doi: 10.1158/2326-6066.CIR-21-0240. Epub 2021 Aug 23. Cancer Immunol Res. 2021. PMID: 34426457 Free PMC article.
ILT2 and ILT4 Drive Myeloid Suppression via Both Overlapping and Distinct Mechanisms.
Tian J, Ashique AM, Weeks S, Lan T, Yang H, Chen HH, Song C, Koyano K, Mondal K, Tsai D, Cheung I, Moshrefi M, Kekatpure A, Fan B, Li B, Qurashi S, Rocha L, Aguayo J, Rodgers C, Meza M, Heeke D, Medfisch SM, Chu C, Starck S, Basak NP, Sankaran S, Malhotra M, Crawley S, Tran TT, Duey DY, Ho C, Mikaelian I, Liu W, Rivera LB, Huang J, Paavola KJ, O'Hollaren K, Blum LK, Lin VY, Chen P, Iyer A, He S, Roda JM, Wang Y, Sissons J, Kutach AK, Kaplan DD, Stone GW. Tian J, et al. Among authors: chen hh, chen p. Cancer Immunol Res. 2024 May 2;12(5):592-613. doi: 10.1158/2326-6066.CIR-23-0568. Cancer Immunol Res. 2024. PMID: 38393969
LEAP2 Is an Endogenous Antagonist of the Ghrelin Receptor.
Ge X, Yang H, Bednarek MA, Galon-Tilleman H, Chen P, Chen M, Lichtman JS, Wang Y, Dalmas O, Yin Y, Tian H, Jermutus L, Grimsby J, Rondinone CM, Konkar A, Kaplan DD. Ge X, et al. Among authors: chen m, chen p. Cell Metab. 2018 Feb 6;27(2):461-469.e6. doi: 10.1016/j.cmet.2017.10.016. Epub 2017 Dec 7. Cell Metab. 2018. PMID: 29233536 Free article.
RasGRP3 Mediates MAPK Pathway Activation in GNAQ Mutant Uveal Melanoma.
Chen X, Wu Q, Depeille P, Chen P, Thornton S, Kalirai H, Coupland SE, Roose JP, Bastian BC. Chen X, et al. Among authors: chen p. Cancer Cell. 2017 May 8;31(5):685-696.e6. doi: 10.1016/j.ccell.2017.04.002. Cancer Cell. 2017. PMID: 28486107 Free PMC article.
Does pasteurization inactivate bird flu virus in milk?
Cui P, Zhuang Y, Zhang Y, Chen L, Chen P, Li J, Feng L, Chen Q, Meng F, Yang H, Jiang Y, Deng G, Shi J, Chen H, Kong H. Cui P, et al. Among authors: chen p. Emerg Microbes Infect. 2024 Jun 4:2364732. doi: 10.1080/22221751.2024.2364732. Online ahead of print. Emerg Microbes Infect. 2024. PMID: 38832658
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