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Anti-tumor activity of a novel LAIR1 antagonist in combination with anti-PD-1 to treat collagen-rich solid tumors.
Rodriguez BL, Huang J, Gibson L, Fradette JJ, Chen HH, Koyano K, Cortez C, Li B, Ho C, Ashique AM, Lin VY, Crawley S, Roda JM, Chen P, Fan B, Kim J, Sissons J, Sitrin J, Kaplan DD, Gibbons DL, Rivera LB. Rodriguez BL, et al. Among authors: roda jm. Mol Cancer Ther. 2024 Apr 22. doi: 10.1158/1535-7163.MCT-23-0866. Online ahead of print. Mol Cancer Ther. 2024. PMID: 38648067
The Fibronectin-ILT3 Interaction Functions as a Stromal Checkpoint that Suppresses Myeloid Cells.
Paavola KJ, Roda JM, Lin VY, Chen P, O'Hollaren KP, Ventura R, Crawley SC, Li B, Chen HH, Malmersjö S, Sharkov NA, Horner G, Guo W, Kutach AK, Mondal K, Zhang Z, Lichtman JS, Song C, Rivera LB, Liu W, Luo J, Wang Y, Solloway MJ, Allan BB, Kekatpure A, Starck SR, Haldankar R, Fan B, Chu C, Tang J, Molgora M, Colonna M, Kaplan DD, Hsu JY. Paavola KJ, et al. Among authors: roda jm. Cancer Immunol Res. 2021 Nov;9(11):1283-1297. doi: 10.1158/2326-6066.CIR-21-0240. Epub 2021 Aug 23. Cancer Immunol Res. 2021. PMID: 34426457 Free PMC article.
ILT2 and ILT4 Drive Myeloid Suppression via Both Overlapping and Distinct Mechanisms.
Tian J, Ashique AM, Weeks S, Lan T, Yang H, Chen HH, Song C, Koyano K, Mondal K, Tsai D, Cheung I, Moshrefi M, Kekatpure A, Fan B, Li B, Qurashi S, Rocha L, Aguayo J, Rodgers C, Meza M, Heeke D, Medfisch SM, Chu C, Starck S, Basak NP, Sankaran S, Malhotra M, Crawley S, Tran TT, Duey DY, Ho C, Mikaelian I, Liu W, Rivera LB, Huang J, Paavola KJ, O'Hollaren K, Blum LK, Lin VY, Chen P, Iyer A, He S, Roda JM, Wang Y, Sissons J, Kutach AK, Kaplan DD, Stone GW. Tian J, et al. Among authors: roda jm. Cancer Immunol Res. 2024 May 2;12(5):592-613. doi: 10.1158/2326-6066.CIR-23-0568. Cancer Immunol Res. 2024. PMID: 38393969
A phase I trial of paclitaxel and trastuzumab in combination with interleukin-12 in patients with HER2/neu-expressing malignancies.
Bekaii-Saab TS, Roda JM, Guenterberg KD, Ramaswamy B, Young DC, Ferketich AK, Lamb TA, Grever MR, Shapiro CL, Carson WE 3rd. Bekaii-Saab TS, et al. Among authors: roda jm. Mol Cancer Ther. 2009 Nov;8(11):2983-91. doi: 10.1158/1535-7163.MCT-09-0820. Epub 2009 Nov 3. Mol Cancer Ther. 2009. PMID: 19887543 Free PMC article. Clinical Trial.
NK Cell-Mediated Antitumor Effects of a Folate-Conjugated Immunoglobulin Are Enhanced by Cytokines.
Jaime-Ramirez AC, McMichael E, Kondadasula S, Skinner CC, Mundy-Bosse BL, Luedke E, Jones NB, Mani A, Roda J, Karpa V, Li H, Li J, Elavazhagan S, La Perle KM, Schmitt AC, Lu Y, Zhang X, Pan X, Mao H, Davis M, Jarjoura D, Butchar JP, Poi M, Phelps M, Tridandapani S, Byrd JC, Caligiuri MA, Lee RJ, Carson WE 3rd. Jaime-Ramirez AC, et al. Cancer Immunol Res. 2016 Apr;4(4):323-336. doi: 10.1158/2326-6066.CIR-15-0168. Epub 2016 Feb 10. Cancer Immunol Res. 2016. PMID: 26865456 Free PMC article.
Correction: Hypoxia-Inducible Factor α Subunits Regulate Tie2-Expressing Macrophages That Influence Tumor Oxygen and Perfusion in Murine Breast Cancer.
Steinberger KJ, Forget MA, Bobko AA, Mihalik NE, Gencheva M, Roda JM, Cole SL, Mo X, Hoblitzell EH, Evans R, Gross AC, Moldovan L, Marsh CB, Khramtsov VV, Eubank TD. Steinberger KJ, et al. Among authors: roda jm. J Immunol. 2020 Dec 1;205(11):3231. doi: 10.4049/jimmunol.2001134. Epub 2020 Oct 28. J Immunol. 2020. PMID: 33115855 Free PMC article. No abstract available.
Hypoxia-Inducible Factor α Subunits Regulate Tie2-Expressing Macrophages That Influence Tumor Oxygen and Perfusion in Murine Breast Cancer.
Steinberger KJ, Forget MA, Bobko AA, Mihalik NE, Gencheva M, Roda JM, Cole SL, Mo X, Hoblitzell EH, Evans R, Gross AC, Moldovan L, Marsh CB, Khramstov VV, Eubank TD. Steinberger KJ, et al. Among authors: roda jm. J Immunol. 2020 Oct 15;205(8):2301-2311. doi: 10.4049/jimmunol.2000185. Epub 2020 Sep 16. J Immunol. 2020. PMID: 32938724 Free PMC article.
124 results