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The IRE1α-XBP1 arm of the unfolded protein response is a host factor activated in SARS-CoV-2 infection.
Fernández JJ, Marín A, Rosales R, Penrice-Randal R, Mlcochova P, Alvarez Y, Villalón-Letelier F, Yildiz S, Pérez E, Rathnasinghe R, Cupic A, Kehrer T, Uccellini MB, Alonso S, Martínez F, McGovern BL, Clark JJ, Sharma P, Bayón Y, Alonso A, Albrecht RA, White KM, Schotsaert M, Miorin L, Stewart JP, Hiscox JA, Gupta RK, Irigoyen N, García-Sastre A, Crespo MS, Fernández N. Fernández JJ, et al. Among authors: rathnasinghe r. Biochim Biophys Acta Mol Basis Dis. 2024 Jun;1870(5):167193. doi: 10.1016/j.bbadis.2024.167193. Epub 2024 Apr 20. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 38648902
Novel influenza A viruses in pigs with zoonotic potential, Chile.
Tapia R, Brito B, Saavedra M, Mena J, García-Salum T, Rathnasinghe R, Barriga G, Tapia K, García V, Bucarey S, Jang Y, Wentworth D, Torremorell M, Neira V, Medina RA. Tapia R, et al. Among authors: rathnasinghe r. Microbiol Spectr. 2024 Apr 2;12(4):e0218123. doi: 10.1128/spectrum.02181-23. Epub 2024 Mar 7. Microbiol Spectr. 2024. PMID: 38446039 Free PMC article.
Self-amplifying mRNA seasonal influenza vaccines elicit mouse neutralizing antibody and cell-mediated immunity and protect ferrets.
Cheung M, Chang C, Rathnasinghe R, Rossignol E, Zhang Y, Ferrari A, Patel H, Huang Y, Sanchez Guillen M, Scalzo T, Lee C, Otten GR, Settembre EC, Music N, Palladino G, Wen Y. Cheung M, et al. Among authors: rathnasinghe r. NPJ Vaccines. 2023 Oct 4;8(1):150. doi: 10.1038/s41541-023-00747-2. NPJ Vaccines. 2023. PMID: 37794051 Free PMC article.
Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis.
Kehrer T, Cupic A, Ye C, Yildiz S, Bouhaddou M, Crossland NA, Barrall EA, Cohen P, Tseng A, Çağatay T, Rathnasinghe R, Flores D, Jangra S, Alam F, Mena I, Aslam S, Saqi A, Rutkowska M, Ummadi MR, Pisanelli G, Richardson RB, Veit EC, Fabius JM, Soucheray M, Polacco BJ, Ak B, Marin A, Evans MJ, Swaney DL, Gonzalez-Reiche AS, Sordillo EM, van Bakel H, Simon V, Zuliani-Alvarez L, Fontoura BMA, Rosenberg BR, Krogan NJ, Martinez-Sobrido L, García-Sastre A, Miorin L. Kehrer T, et al. Among authors: rathnasinghe r. Cell Host Microbe. 2023 Oct 11;31(10):1668-1684.e12. doi: 10.1016/j.chom.2023.08.003. Epub 2023 Sep 21. Cell Host Microbe. 2023. PMID: 37738983 Free article.
A multicomponent intranasal adjuvant drives durable humoral, cellular, and mucosal immune responses to SARS-CoV-2 in young and aged mice.
Jangra S, Landers JJ, Laghlali G, Rathnasinghe R, O'Konek JJ, Janczak KW, García-Sastre A, Baker JR Jr, Schotsaert M, Wong PT. Jangra S, et al. Among authors: rathnasinghe r. Res Sq [Preprint]. 2023 Jan 20:rs.3.rs-2457013. doi: 10.21203/rs.3.rs-2457013/v1. Res Sq. 2023. PMID: 36711479 Free PMC article. Updated. Preprint.
Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis.
Kehrer T, Cupic A, Ye C, Yildiz S, Bouhhadou M, Crossland NA, Barrall E, Cohen P, Tseng A, Çağatay T, Rathnasinghe R, Flores D, Jangra S, Alam F, Mena N, Aslam S, Saqi A, Marin A, Rutkowska M, Ummadi MR, Pisanelli G, Richardson RB, Veit EC, Fabius JM, Soucheray M, Polacco BJ, Evans MJ, Swaney DL, Gonzalez-Reiche AS, Sordillo EM, van Bakel H, Simon V, Zuliani-Alvarez L, Fontoura BMA, Rosenberg BR, Krogan NJ, Martinez-Sobrido L, García-Sastre A, Miorin L. Kehrer T, et al. Among authors: rathnasinghe r. bioRxiv [Preprint]. 2022 Nov 30:2022.10.18.512708. doi: 10.1101/2022.10.18.512708. bioRxiv. 2022. PMID: 36299428 Free PMC article. Updated. Preprint.
48 results