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The IRE1α-XBP1 arm of the unfolded protein response is a host factor activated in SARS-CoV-2 infection.
Fernández JJ, Marín A, Rosales R, Penrice-Randal R, Mlcochova P, Alvarez Y, Villalón-Letelier F, Yildiz S, Pérez E, Rathnasinghe R, Cupic A, Kehrer T, Uccellini MB, Alonso S, Martínez F, McGovern BL, Clark JJ, Sharma P, Bayón Y, Alonso A, Albrecht RA, White KM, Schotsaert M, Miorin L, Stewart JP, Hiscox JA, Gupta RK, Irigoyen N, García-Sastre A, Crespo MS, Fernández N. Fernández JJ, et al. Among authors: rosales r. Biochim Biophys Acta Mol Basis Dis. 2024 Jun;1870(5):167193. doi: 10.1016/j.bbadis.2024.167193. Epub 2024 Apr 20. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 38648902
Plitidepsin has a positive therapeutic index in adult patients with COVID-19 requiring hospitalization.
Varona JF, Landete P, Lopez-Martin JA, Estrada V, Paredes R, Guisado-Vasco P, de Orueta LF, Torralba M, Fortún J, Vates R, Barberán J, Clotet B, Ancochea J, Carnevali D, Cabello N, Porras L, Gijón P, Monereo A, Abad D, Zúñiga S, Sola I, Rodon J, Izquierdo-Useros N, Fudio S, Pontes MJ, de Rivas B, Girón de Velasco P, Sopesén B, Nieto A, Gómez J, Avilés P, Lubomirov R, White KM, Rosales R, Yildiz S, Reuschl AK, Thorne LG, Jolly C, Towers GJ, Zuliani-Alvarez L, Bouhaddou M, Obernier K, Enjuanes L, Fernández-Sousa JM; Plitidepsin – COVID - 19 Study Group; Krogan NJ, Jimeno JM, García-Sastre A. Varona JF, et al. Among authors: rosales r. medRxiv [Preprint]. 2021 May 25:2021.05.25.21257505. doi: 10.1101/2021.05.25.21257505. medRxiv. 2021. PMID: 34075384 Free PMC article. Updated. Preprint.
Tracking SARS-CoV-2 variants of concern in wastewater: an assessment of nine computational tools using simulated genomic data.
Sutcliffe SG, Kraemer SA, Ellmen I, Knapp JJ, Overton AK, Nash D, Nissimov JI, Charles TC, Dreifuss D, Topolsky I, Baykal PI, Fuhrmann L, Jablonski KP, Beerenwinkel N, Levy JI, Olabode AS, Becker DG, Gugan G, Brintnell E, Poon AFY, Valieris R, Drummond RD, Defelicibus A, Dias-Neto E, Rosales RA, Tojal da Silva I, Orfanou A, Psomopoulos F, Pechlivanis N, Pipes L, Chen Z, Baaijens JA, Baym M, Shapiro BJ. Sutcliffe SG, et al. Among authors: rosales ra. Microb Genom. 2024 May;10(5). doi: 10.1099/mgen.0.001249. Microb Genom. 2024. PMID: 38785221
Angiopoietin-2, vascular endothelial growth factor family, and heparin binding endothelial growth factor are associated with subclinical atherosclerosis in rheumatoid arthritis.
Pàmies A, Llop D, Ibarretxe D, Rosales R, Masana L, Vallvé JC, Paredes S. Pàmies A, et al. Among authors: rosales r. Comput Struct Biotechnol J. 2024 Apr 16;23:1680-1688. doi: 10.1016/j.csbj.2024.04.042. eCollection 2024 Dec. Comput Struct Biotechnol J. 2024. PMID: 38689721 Free PMC article.
Stability of Mosaic Divergent Repeat Interruptions in X-Linked Dystonia-Parkinsonism.
Laß J, Lüth T, Schlüter K, Schaake S, Laabs BH, Much C, Jamora RD, Rosales RL, Saranza G, Diesta CCE, Pearson CE, König IR, Brüggemann N, Klein C, Westenberger A, Trinh J. Laß J, et al. Among authors: rosales rl. Mov Disord. 2024 Apr 14. doi: 10.1002/mds.29809. Online ahead of print. Mov Disord. 2024. PMID: 38616406
Minimal Quantization Model in Pilot-Wave Hydrodynamics.
Blitstein AM, Rosales RR, Sáenz PJ. Blitstein AM, et al. Among authors: rosales rr. Phys Rev Lett. 2024 Mar 8;132(10):104003. doi: 10.1103/PhysRevLett.132.104003. Phys Rev Lett. 2024. PMID: 38518309
495 results