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Prospective de novo drug design with deep interactome learning.
Atz K, Cotos L, Isert C, Håkansson M, Focht D, Hilleke M, Nippa DF, Iff M, Ledergerber J, Schiebroek CCG, Romeo V, Hiss JA, Merk D, Schneider P, Kuhn B, Grether U, Schneider G. Atz K, et al. Among authors: kuhn b. Nat Commun. 2024 Apr 22;15(1):3408. doi: 10.1038/s41467-024-47613-w. Nat Commun. 2024. PMID: 38649351 Free PMC article.
New Insights on the mechanism of PPAR-targeted drugs.
Grether U, Klaus W, Kuhn B, Maerki HP, Mohr P, Wright MB. Grether U, et al. Among authors: kuhn b. ChemMedChem. 2010 Dec 3;5(12):1973-6. doi: 10.1002/cmdc.201000446. ChemMedChem. 2010. PMID: 21069658 No abstract available.
Identification of (R)-[18F]YH134 for Monoacylglycerol Lipase Neuroimaging and Exploration of Its Use for Central Nervous System and Peripheral Drug Development.
He Y, Krämer SD, Grether U, Wittwer MB, Collin L, Kuhn B, Topp A, Heer D, O'Hara F, Honer M, Pavlovic A, Richter H, Ritter M, Rombach D, Keller C, Gobbi L, Mu L. He Y, et al. Among authors: kuhn b. J Nucl Med. 2024 Feb 1;65(2):300-305. doi: 10.2967/jnumed.123.266426. J Nucl Med. 2024. PMID: 38164615
Discovery, synthesis and evaluation of novel reversible monoacylglycerol lipase radioligands bearing a morpholine-3-one scaffold.
He Y, Gobbi LC, Herde AM, Rombach D, Ritter M, Kuhn B, Wittwer MB, Heer D, Hornsperger B, Bell C, O'Hara F, Benz J, Honer M, Keller C, Collin L, Richter H, Schibli R, Grether U, Mu L. He Y, et al. Among authors: kuhn b. Nucl Med Biol. 2022 May-Jun;108-109:24-32. doi: 10.1016/j.nucmedbio.2022.02.002. Epub 2022 Feb 23. Nucl Med Biol. 2022. PMID: 35248850 Free article.
513 results