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341 results

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Page 1
Proximally biased V(D)J recombination in the clonal evolution of IGH alleles in KMT2A::AFF1 BCP-ALL of all age classes.
Müller H, Dicker F, Bär C, Walter W, Hutter S, Nadarajah N, Meggendorfer M, Gao Q, Iacobucci I, Mullighan CG, Kern W, Haferlach T, Haferlach C. Müller H, et al. Among authors: mullighan cg. Hemasphere. 2024 Apr 22;8(4):e71. doi: 10.1002/hem3.71. eCollection 2024 Apr. Hemasphere. 2024. PMID: 38650597 Free PMC article. No abstract available.
Stromal-induced epithelial-mesenchymal transition induces targetable drug resistance in acute lymphoblastic leukemia.
Park CS, Yoshihara H, Gao Q, Qu C, Iacobucci I, Ghate PS, Connelly JP, Pruett-Miller SM, Wagner B, Robinson CG, Mishra A, Peng J, Yang L, Rankovic Z, Finkelstein D, Luger S, Litzow M, Paietta EM, Hebbar N, Velasquez MP, Mullighan CG. Park CS, et al. Among authors: mullighan cg. Cell Rep. 2023 Jul 25;42(7):112804. doi: 10.1016/j.celrep.2023.112804. Epub 2023 Jul 14. Cell Rep. 2023. PMID: 37453060 Free PMC article.
CASZ1 upregulates PI3K-AKT-mTOR signaling and promotes T-cell acute lymphoblastic leukemia.
Cardoso BA, Duque M, Gírio A, Fragoso R, Oliveira ML, Allen JR, Martins LR, Correia NC, Silveira AB, Veloso A, Kimura S, Demoen L, Matthijssens F, Jeha S, Cheng C, Pui CH, Grosso AR, Neto JL, De Almeida SF, Van Vlieberghe P, Mullighan CG, Yunes JA, Langenau DM, Pflumio F, Barata JT. Cardoso BA, et al. Among authors: mullighan cg. Haematologica. 2023 Dec 7. doi: 10.3324/haematol.2023.282854. Online ahead of print. Haematologica. 2023. PMID: 38058200 Free article.
Elevated enhancer-oncogene contacts and higher oncogene expression levels by recurrent CTCF inactivating mutations in acute T cell leukemia.
Smits WK, Vermeulen C, Hagelaar R, Kimura S, Vroegindeweij EM, Buijs-Gladdines JGCAM, van de Geer E, Verstegen MJAM, Splinter E, van Reijmersdal SV, Buijs A, Galjart N, van Eyndhoven W, van Min M, Kuiper R, Kemmeren P, Mullighan CG, de Laat W, Meijerink JPP. Smits WK, et al. Among authors: mullighan cg. Cell Rep. 2023 Apr 25;42(4):112373. doi: 10.1016/j.celrep.2023.112373. Epub 2023 Apr 14. Cell Rep. 2023. PMID: 37060567 Free PMC article.
Association of leukemic molecular profile with efficacy of inotuzumab ozogamicin in adults with relapsed/refractory ALL.
Zhao Y, Laird AD, Roberts KG, Yafawi RL, Kantarjian HM, DeAngelo DJ, Stelljes M, Liedtke M, Stock W, Gökbuget N, O'Brien SM, Jabbour EJ, Cassaday RD, Loyd MR, Olsen SR, Neale GA, Liu X, Vandendries E, Advani AS, Mullighan CG. Zhao Y, et al. Among authors: mullighan cg. Blood Adv. 2024 Mar 26:bloodadvances.2023012430. doi: 10.1182/bloodadvances.2023012430. Online ahead of print. Blood Adv. 2024. PMID: 38607410
Genomic determinants of response and resistance to inotuzumab ozogamicin in B-cell ALL.
Zhao Y, Short NJ, Kantarjian HM, Chang TC, Ghate PS PhD, Qu C, Macaron W, Jain N, Thakral B, Phillips A, Khoury JD, Garcia-Manero G, Zhang W, Fan Y, Yang H, Garris R, Nasr LF, Kriwacki R, Roberts KG, Konopleva MY, Jabbour EJ, Mullighan CG. Zhao Y, et al. Among authors: mullighan cg. Blood. 2024 Mar 29:blood.2024023930. doi: 10.1182/blood.2024023930. Online ahead of print. Blood. 2024. PMID: 38551807
A lineage-specific STAT5BN642H mouse model to study NK-cell leukemia.
Klein K, Kollmann S, Hiesinger A, List J, Kendler J, Klampfl T, Randhawa M, Trifinopoulos J, Maurer B, Grausenburger R, Bertram CA, Moriggl RH, Rülicke T, Mullighan CG, Witalisz-Siepracka A, Walter W, Hoermann G, Sexl V, Gotthardt D. Klein K, et al. Among authors: mullighan cg. Blood. 2024 Mar 18:blood.2023022655. doi: 10.1182/blood.2023022655. Online ahead of print. Blood. 2024. PMID: 38498036 Free article.
Enhanced Risk Stratification for Children and Young Adults with B-Cell Acute Lymphoblastic Leukemia: A Children's Oncology Group Report.
DelRocco NJ, Loh ML, Borowitz MJ, Gupta S, Rabin KR, Zweidler-McKay P, Maloney KW, Mattano LA, Larsen E, Angiolillo A, Schore RJ, Burke MJ, Salzer WL, Wood BL, Carroll AJ, Heerema NA, Reshmi SC, Gastier-Foster JM, Harvey R, Chen IM, Roberts KG, Mullighan CG, Willman C, Winick N, Carroll WL, Rau RE, Teachey DT, Hunger SP, Raetz EA, Devidas M, Kairalla JA. DelRocco NJ, et al. Among authors: mullighan cg. Leukemia. 2024 Apr;38(4):720-728. doi: 10.1038/s41375-024-02166-1. Epub 2024 Feb 15. Leukemia. 2024. PMID: 38360863 Free PMC article.
Precise single-cell transcriptomic mapping of normal and leukemic cell states reveals unconventional lineage priming in acute myeloid leukemia.
Zeng AGX, Iacobucci I, Shah S, Mitchell A, Wong G, Bansal S, Gao Q, Kim H, Kennedy JA, Minden MD, Haferlach T, Mullighan CG, Dick JE. Zeng AGX, et al. Among authors: mullighan cg. bioRxiv [Preprint]. 2023 Dec 27:2023.12.26.573390. doi: 10.1101/2023.12.26.573390. bioRxiv. 2023. PMID: 38234771 Free PMC article. Preprint.
Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines.
Nishiguchi G, Mascibroda LG, Young SM, Caine EA, Abdelhamed S, Kooijman JJ, Miller DJ, Das S, McGowan K, Mayasundari A, Shi Z, Barajas JM, Hiltenbrand R, Aggarwal A, Chang Y, Mishra V, Narina S, Thomas M, Loughran AJ, Kalathur R, Yu K, Zhou S, Wang X, High AA, Peng J, Pruett-Miller SM, Daniels DL, Urh M, Shelat AA, Mullighan CG, Riching KM, Zaman GJR, Fischer M, Klco JM, Rankovic Z. Nishiguchi G, et al. Among authors: mullighan cg. Nat Commun. 2024 Jan 16;15(1):482. doi: 10.1038/s41467-024-44698-1. Nat Commun. 2024. PMID: 38228616 Free PMC article.
341 results