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The discovery and development of gefapixant.
Ford AP, Dillon MP, Kitt MM, Gever JR. Ford AP, et al. Among authors: kitt mm. Auton Neurosci. 2021 Nov;235:102859. doi: 10.1016/j.autneu.2021.102859. Epub 2021 Jul 31. Auton Neurosci. 2021. PMID: 34403981
Gefapixant, a P2X3 receptor antagonist, for the treatment of refractory or unexplained chronic cough: a randomised, double-blind, controlled, parallel-group, phase 2b trial.
Smith JA, Kitt MM, Morice AH, Birring SS, McGarvey LP, Sher MR, Li YP, Wu WC, Xu ZJ, Muccino DR, Ford AP; Protocol 012 Investigators. Smith JA, et al. Among authors: kitt mm. Lancet Respir Med. 2020 Aug;8(8):775-785. doi: 10.1016/S2213-2600(19)30471-0. Epub 2020 Feb 25. Lancet Respir Med. 2020. PMID: 32109425 Clinical Trial.
Author response: The human cough reflex has separate, distinct pathways.
Morice AH, Kitt MM, Ford AP, Tershakovec AM, Wu WC, Brindle K, Thompson R, Thackray-Nocera S, Wright C. Morice AH, et al. Among authors: kitt mm. Eur Respir J. 2020 Feb 6;55(2):1902312. doi: 10.1183/13993003.02312-2019. Print 2020 Feb. Eur Respir J. 2020. PMID: 32029646 Free article. No abstract available.
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