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Discovery of C-Linked Nucleoside Analogues with Antiviral Activity against SARS-CoV-2.
ACS Infect Dis. 2024 May 10;10(5):1780-1792. doi: 10.1021/acsinfecdis.4c00122. Epub 2024 Apr 23.
ACS Infect Dis. 2024.
PMID: 38651692
The ghrelin O-acyltransferase structure reveals a catalytic channel for transmembrane hormone acylation.
Campaña MB, Irudayanathan FJ, Davis TR, McGovern-Gooch KR, Loftus R, Ashkar M, Escoffery N, Navarro M, Sieburg MA, Nangia S, Hougland JL.
Campaña MB, et al. Among authors: mcgovern gooch kr.
J Biol Chem. 2019 Sep 27;294(39):14166-14174. doi: 10.1074/jbc.AC119.009749. Epub 2019 Aug 14.
J Biol Chem. 2019.
PMID: 31413115
Free PMC article.
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Fluorescence-based investigations of RNA-small molecule interactions.
McGovern-Gooch KR, Baird NJ.
McGovern-Gooch KR, et al.
Methods. 2019 Sep 1;167:54-65. doi: 10.1016/j.ymeth.2019.05.017. Epub 2019 May 23.
Methods. 2019.
PMID: 31129289
Free PMC article.
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Finely tuned conformational dynamics regulate the protective function of the lncRNA MALAT1 triple helix.
Ageeli AA, McGovern-Gooch KR, Kaminska MM, Baird NJ.
Ageeli AA, et al. Among authors: mcgovern gooch kr.
Nucleic Acids Res. 2019 Feb 20;47(3):1468-1481. doi: 10.1093/nar/gky1171.
Nucleic Acids Res. 2019.
PMID: 30462290
Free PMC article.
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The octanoylated energy regulating hormone ghrelin: An expanded view of ghrelin's biological interactions and avenues for controlling ghrelin signaling.
Cleverdon ER, McGovern-Gooch KR, Hougland JL.
Cleverdon ER, et al. Among authors: mcgovern gooch kr.
Mol Membr Biol. 2016 Sep-Dec;33(6-8):111-124. doi: 10.1080/09687688.2017.1388930. Epub 2017 Nov 16.
Mol Membr Biol. 2016.
PMID: 29143554
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Synthetic Triterpenoid Inhibition of Human Ghrelin O-Acyltransferase: The Involvement of a Functionally Required Cysteine Provides Mechanistic Insight into Ghrelin Acylation.
McGovern-Gooch KR, Mahajani NS, Garagozzo A, Schramm AJ, Hannah LG, Sieburg MA, Chisholm JD, Hougland JL.
McGovern-Gooch KR, et al.
Biochemistry. 2017 Feb 21;56(7):919-931. doi: 10.1021/acs.biochem.6b01008. Epub 2017 Feb 7.
Biochemistry. 2017.
PMID: 28134508
Free PMC article.
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Ghrelin Octanoylation Is Completely Stabilized in Biological Samples by Alkyl Fluorophosphonates.
McGovern-Gooch KR, Rodrigues T, Darling JE, Sieburg MA, Abizaid A, Hougland JL.
McGovern-Gooch KR, et al.
Endocrinology. 2016 Nov;157(11):4330-4338. doi: 10.1210/en.2016-1657. Epub 2016 Sep 13.
Endocrinology. 2016.
PMID: 27623288
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