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HSV-1 employs UL56 to antagonize expression and function of cGAMP channels.
Blest HTW, Redmond A, Avissar J, Barker J, Bridgeman A, Fowler G, Chauveau L, Hertzog J, Vendrell I, Fischer R, Iversen MB, Jing L, Koelle DM, Paludan SR, Kessler BM, Crump CM, Rehwinkel J. Blest HTW, et al. Among authors: rehwinkel j. Cell Rep. 2024 May 28;43(5):114122. doi: 10.1016/j.celrep.2024.114122. Epub 2024 Apr 22. Cell Rep. 2024. PMID: 38652659 Free article.
Regulation and inhibition of the DNA sensor cGAS.
Hertzog J, Rehwinkel J. Hertzog J, et al. Among authors: rehwinkel j. EMBO Rep. 2020 Dec 3;21(12):e51345. doi: 10.15252/embr.202051345. Epub 2020 Nov 5. EMBO Rep. 2020. PMID: 33155371 Free PMC article. Review.
The RNA sensor MDA5 detects SARS-CoV-2 infection.
Sampaio NG, Chauveau L, Hertzog J, Bridgeman A, Fowler G, Moonen JP, Dupont M, Russell RA, Noerenberg M, Rehwinkel J. Sampaio NG, et al. Among authors: rehwinkel j. Sci Rep. 2021 Jul 1;11(1):13638. doi: 10.1038/s41598-021-92940-3. Sci Rep. 2021. PMID: 34211037 Free PMC article.
Interferon induction held captive in tumor cells.
Bridgeman A, Rehwinkel J. Bridgeman A, et al. Among authors: rehwinkel j. Mol Cell. 2021 Oct 21;81(20):4109-4110. doi: 10.1016/j.molcel.2021.10.004. Mol Cell. 2021. PMID: 34686311 Free article.
Inclusion of cGAMP within virus-like particle vaccines enhances their immunogenicity.
Chauveau L, Bridgeman A, Tan TK, Beveridge R, Frost JN, Rijal P, Pedroza-Pacheco I, Partridge T, Gilbert-Jaramillo J, Knight ML, Liu X, Russell RA, Borrow P, Drakesmith H, Townsend AR, Rehwinkel J. Chauveau L, et al. Among authors: rehwinkel j. EMBO Rep. 2021 Aug 4;22(8):e52447. doi: 10.15252/embr.202152447. Epub 2021 Jun 18. EMBO Rep. 2021. PMID: 34142428 Free PMC article.
Varicella-Zoster virus ORF9 is an antagonist of the DNA sensor cGAS.
Hertzog J, Zhou W, Fowler G, Rigby RE, Bridgeman A, Blest HT, Cursi C, Chauveau L, Davenne T, Warner BE, Kinchington PR, Kranzusch PJ, Rehwinkel J. Hertzog J, et al. Among authors: rehwinkel j. EMBO J. 2022 Jul 18;41(14):e109217. doi: 10.15252/embj.2021109217. Epub 2022 Jun 7. EMBO J. 2022. PMID: 35670106 Free PMC article.
91 results