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Stimulating intestinal GIP release reduces food intake and body weight in mice.
Lewis JE, Nuzzaci D, James-Okoro PP, Montaner M, O'Flaherty E, Darwish T, Hayashi M, Liberles SD, Hornigold D, Naylor J, Baker D, Gribble FM, Reimann F. Lewis JE, et al. Among authors: darwish t. Mol Metab. 2024 Jun;84:101945. doi: 10.1016/j.molmet.2024.101945. Epub 2024 Apr 21. Mol Metab. 2024. PMID: 38653401 Free PMC article.
Glucose-Dependent Insulinotropic Polypeptide Receptor-Expressing Cells in the Hypothalamus Regulate Food Intake.
Adriaenssens AE, Biggs EK, Darwish T, Tadross J, Sukthankar T, Girish M, Polex-Wolf J, Lam BY, Zvetkova I, Pan W, Chiarugi D, Yeo GSH, Blouet C, Gribble FM, Reimann F. Adriaenssens AE, et al. Among authors: darwish t. Cell Metab. 2019 Nov 5;30(5):987-996.e6. doi: 10.1016/j.cmet.2019.07.013. Epub 2019 Aug 22. Cell Metab. 2019. PMID: 31447324 Free PMC article.
Behavioural and neurochemical mechanisms underpinning the feeding-suppressive effect of GLP-1/CCK combinatorial therapy.
Roth E, Benoit S, Quentin B, Lam B, Will S, Ma M, Heeley N, Darwish T, Shrestha Y, Gribble F, Reimann F, Pshenichnaya I, Yeo G, Baker DJ, Trevaskis JL, Blouet C. Roth E, et al. Among authors: darwish t. Mol Metab. 2021 Jan;43:101118. doi: 10.1016/j.molmet.2020.101118. Epub 2020 Nov 19. Mol Metab. 2021. PMID: 33221554 Free PMC article.
Characterisation of proguanylin expressing cells in the intestine - evidence for constitutive luminal secretion.
Dye FS, Larraufie P, Kay R, Darwish T, Rievaj J, Goldspink DA, Meek CL, Middleton SJ, Hardwick RH, Roberts GP, Percival-Alwyn JL, Vaughan T, Ferraro F, Challis BG, O'Rahilly S, Groves M, Gribble FM, Reimann F. Dye FS, et al. Among authors: darwish t. Sci Rep. 2019 Oct 30;9(1):15574. doi: 10.1038/s41598-019-52049-0. Sci Rep. 2019. PMID: 31666564 Free PMC article.
137 results