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A flow cytometry-based protocol for syngenic isolation of neurovascular unit cells from mouse and human tissues.
Spitzer D, Khel MI, Pütz T, Zinke J, Jia X, Sommer K, Filipski K, Thorsen F, Freiman TM, Günther S, Plate KH, Harter PN, Liebner S, Reiss Y, Di Tacchio M, Guérit S, Devraj K. Spitzer D, et al. Among authors: devraj k. Nat Protoc. 2023 May;18(5):1510-1542. doi: 10.1038/s41596-023-00805-y. Epub 2023 Mar 1. Nat Protoc. 2023. PMID: 36859615 Review.
TGF-Beta Modulates the Integrity of the Blood Brain Barrier In Vitro, and Is Associated with Metabolic Alterations in Pericytes.
Schumacher L, Slimani R, Zizmare L, Ehlers J, Kleine Borgmann F, Fitzgerald JC, Fallier-Becker P, Beckmann A, Grißmer A, Meier C, El-Ayoubi A, Devraj K, Mittelbronn M, Trautwein C, Naumann U. Schumacher L, et al. Among authors: devraj k. Biomedicines. 2023 Jan 14;11(1):214. doi: 10.3390/biomedicines11010214. Biomedicines. 2023. PMID: 36672722 Free PMC article.
The neurovasculature as a target in temporal lobe epilepsy.
Reiss Y, Bauer S, David B, Devraj K, Fidan E, Hattingen E, Liebner S, Melzer N, Meuth SG, Rosenow F, Rüber T, Willems LM, Plate KH. Reiss Y, et al. Among authors: devraj k. Brain Pathol. 2023 Mar;33(2):e13147. doi: 10.1111/bpa.13147. Epub 2023 Jan 4. Brain Pathol. 2023. PMID: 36599709 Free PMC article. Review.
Profiling the neurovascular unit unveils detrimental effects of osteopontin on the blood-brain barrier in acute ischemic stroke.
Spitzer D, Guérit S, Puetz T, Khel MI, Armbrust M, Dunst M, Macas J, Zinke J, Devraj G, Jia X, Croll F, Sommer K, Filipski K, Freiman TM, Looso M, Günther S, Di Tacchio M, Plate KH, Reiss Y, Liebner S, Harter PN, Devraj K. Spitzer D, et al. Among authors: devraj k. Acta Neuropathol. 2022 Aug;144(2):305-337. doi: 10.1007/s00401-022-02452-1. Epub 2022 Jun 25. Acta Neuropathol. 2022. PMID: 35752654 Free PMC article.
The splicing-regulatory lncRNA NTRAS sustains vascular integrity.
Fouani Y, Kirchhof L, Stanicek L, Luxán G, Heumüller AW, Knau A, Fischer A, Devraj K, John D, Neumann P, Bindereif A, Boon RA, Liebner S, Wittig I, Mogler C, Karimova M, Dimmeler S, Jaé N. Fouani Y, et al. Among authors: devraj k. EMBO Rep. 2022 Jun 7;23(6):e54157. doi: 10.15252/embr.202154157. Epub 2022 May 8. EMBO Rep. 2022. PMID: 35527520 Free PMC article.
Engineered Wnt ligands enable blood-brain barrier repair in neurological disorders.
Martin M, Vermeiren S, Bostaille N, Eubelen M, Spitzer D, Vermeersch M, Profaci CP, Pozuelo E, Toussay X, Raman-Nair J, Tebabi P, America M, De Groote A, Sanderson LE, Cabochette P, Germano RFV, Torres D, Boutry S, de Kerchove d'Exaerde A, Bellefroid EJ, Phoenix TN, Devraj K, Lacoste B, Daneman R, Liebner S, Vanhollebeke B. Martin M, et al. Among authors: devraj k. Science. 2022 Feb 18;375(6582):eabm4459. doi: 10.1126/science.abm4459. Epub 2022 Feb 18. Science. 2022. PMID: 35175798
44 results