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Structural Pharmacology of TRPV4 Antagonists.
Fan J, Guo C, Liao D, Ke H, Lei J, Xie W, Tang Y, Tominaga M, Huang Z, Lei X. Fan J, et al. Among authors: huang z. Adv Sci (Weinh). 2024 Apr 24:e2401583. doi: 10.1002/advs.202401583. Online ahead of print. Adv Sci (Weinh). 2024. PMID: 38659239
N-type fast inactivation of a eukaryotic voltage-gated sodium channel.
Zhang J, Shi Y, Fan J, Chen H, Xia Z, Huang B, Jiang J, Gong J, Huang Z, Jiang D. Zhang J, et al. Among authors: huang b, huang z. Nat Commun. 2022 May 17;13(1):2713. doi: 10.1038/s41467-022-30400-w. Nat Commun. 2022. PMID: 35581266 Free PMC article.
Structural basis of human Slo2.2 channel gating and modulation.
Zhang J, Liu S, Fan J, Yan R, Huang B, Zhou F, Yuan T, Gong J, Huang Z, Jiang D. Zhang J, et al. Among authors: huang b, huang z. Cell Rep. 2023 Aug 29;42(8):112858. doi: 10.1016/j.celrep.2023.112858. Epub 2023 Jul 25. Cell Rep. 2023. PMID: 37494189 Free article.
Structure, gating, and pharmacology of human CaV3.3 channel.
He L, Yu Z, Geng Z, Huang Z, Zhang C, Dong Y, Gao Y, Wang Y, Chen Q, Sun L, Ma X, Huang B, Wang X, Zhao Y. He L, et al. Among authors: huang b, huang z. Nat Commun. 2022 Apr 19;13(1):2084. doi: 10.1038/s41467-022-29728-0. Nat Commun. 2022. PMID: 35440630 Free PMC article.
Structural basis for NaV1.7 inhibition by pore blockers.
Zhang J, Shi Y, Huang Z, Li Y, Yang B, Gong J, Jiang D. Zhang J, et al. Among authors: huang z. Nat Struct Mol Biol. 2022 Dec;29(12):1208-1216. doi: 10.1038/s41594-022-00860-1. Epub 2022 Nov 24. Nat Struct Mol Biol. 2022. PMID: 36424527
Structural bases of inhibitory mechanism of CaV1.2 channel inhibitors.
Wei Y, Yu Z, Wang L, Li X, Li N, Bai Q, Wang Y, Li R, Meng Y, Xu H, Wang X, Dong Y, Huang Z, Zhang XC, Zhao Y. Wei Y, et al. Among authors: huang z. Nat Commun. 2024 Mar 30;15(1):2772. doi: 10.1038/s41467-024-47116-8. Nat Commun. 2024. PMID: 38555290 Free PMC article.
Structural mechanism of voltage-gated sodium channel slow inactivation.
Chen H, Xia Z, Dong J, Huang B, Zhang J, Zhou F, Yan R, Shi Y, Gong J, Jiang J, Huang Z, Jiang D. Chen H, et al. Among authors: huang b, huang z. Nat Commun. 2024 May 1;15(1):3691. doi: 10.1038/s41467-024-48125-3. Nat Commun. 2024. PMID: 38693179 Free PMC article.
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