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Robust self-supervised denoising of voltage imaging data using CellMincer.
Wang B, Ma T, Chen T, Nguyen T, Crouse E, Fleming SJ, Walker AS, Valakh V, Nehme R, Miller EW, Farhi SL, Babadi M. Wang B, et al. Among authors: nehme r. bioRxiv [Preprint]. 2024 Apr 15:2024.04.12.589298. doi: 10.1101/2024.04.12.589298. bioRxiv. 2024. PMID: 38659950 Free PMC article. Preprint.
Robust induction of functional astrocytes using NGN2 expression in human pluripotent stem cells.
Berryer MH, Tegtmeyer M, Binan L, Valakh V, Nathanson A, Trendafilova D, Crouse E, Klein JA, Meyer D, Pietiläinen O, Rapino F, Farhi SL, Rubin LL, McCarroll SA, Nehme R, Barrett LE. Berryer MH, et al. Among authors: nehme r. iScience. 2023 May 30;26(7):106995. doi: 10.1016/j.isci.2023.106995. eCollection 2023 Jul 21. iScience. 2023. PMID: 37534135 Free PMC article.
The 22q11.2 region regulates presynaptic gene-products linked to schizophrenia.
Nehme R, Pietiläinen O, Artomov M, Tegtmeyer M, Valakh V, Lehtonen L, Bell C, Singh T, Trehan A, Sherwood J, Manning D, Peirent E, Malik R, Guss EJ, Hawes D, Beccard A, Bara AM, Hazelbaker DZ, Zuccaro E, Genovese G, Loboda AA, Neumann A, Lilliehook C, Kuismin O, Hamalainen E, Kurki M, Hultman CM, Kähler AK, Paulo JA, Ganna A, Madison J, Cohen B, McPhie D, Adolfsson R, Perlis R, Dolmetsch R, Farhi S, McCarroll S, Hyman S, Neale B, Barrett LE, Harper W, Palotie A, Daly M, Eggan K. Nehme R, et al. Nat Commun. 2022 Jun 27;13(1):3690. doi: 10.1038/s41467-022-31436-8. Nat Commun. 2022. PMID: 35760976 Free PMC article.
Early Alzheimer's disease pathology in human cortex is associated with a transient phase of distinct cell states.
Gazestani V, Kamath T, Nadaf NM, Burris SJ, Rooney B, Junkkari A, Vanderburg C, Rauramaa T, Therrien M, Tegtmeyer M, Herukka SK, Abdulraouf A, Marsh S, Malm T, Hiltunen M, Nehme R, Stevens B, Leinonen V, Macosko EZ. Gazestani V, et al. Among authors: nehme r. bioRxiv [Preprint]. 2023 Jun 5:2023.06.03.543569. doi: 10.1101/2023.06.03.543569. bioRxiv. 2023. PMID: 37333365 Free PMC article. Updated. Preprint.
A systems-biology approach connects aging mechanisms with Alzheimer's disease pathogenesis.
Leventhal MJ, Zanella CA, Kang B, Peng J, Gritsch D, Liao Z, Bukhari H, Wang T, Pao PC, Danquah S, Benetatos J, Nehme R, Farhi S, Tsai LH, Dong X, Scherzer CR, Feany MB, Fraenkel E. Leventhal MJ, et al. Among authors: nehme r. bioRxiv [Preprint]. 2024 Mar 17:2024.03.17.585262. doi: 10.1101/2024.03.17.585262. bioRxiv. 2024. PMID: 38559190 Free PMC article. Preprint.
High-dimensional phenotyping to define the genetic basis of cellular morphology.
Tegtmeyer M, Arora J, Asgari S, Cimini BA, Nadig A, Peirent E, Liyanage D, Way GP, Weisbart E, Nathan A, Amariuta T, Eggan K, Haghighi M, McCarroll SA, O'Connor L, Carpenter AE, Singh S, Nehme R, Raychaudhuri S. Tegtmeyer M, et al. Among authors: nehme r. Nat Commun. 2024 Jan 6;15(1):347. doi: 10.1038/s41467-023-44045-w. Nat Commun. 2024. PMID: 38184653 Free PMC article.
118 results