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Simulation of the Clinical and Pathological Manifestations of Coronavirus Disease 2019 (COVID-19) in a Golden Syrian Hamster Model: Implications for Disease Pathogenesis and Transmissibility.
Chan JF, Zhang AJ, Yuan S, Poon VK, Chan CC, Lee AC, Chan WM, Fan Z, Tsoi HW, Wen L, Liang R, Cao J, Chen Y, Tang K, Luo C, Cai JP, Kok KH, Chu H, Chan KH, Sridhar S, Chen Z, Chen H, To KK, Yuen KY. Chan JF, et al. Among authors: yuan s. Clin Infect Dis. 2020 Dec 3;71(9):2428-2446. doi: 10.1093/cid/ciaa325. Clin Infect Dis. 2020. PMID: 32215622 Free PMC article.
Comparative Replication and Immune Activation Profiles of SARS-CoV-2 and SARS-CoV in Human Lungs: An Ex Vivo Study With Implications for the Pathogenesis of COVID-19.
Chu H, Chan JF, Wang Y, Yuen TT, Chai Y, Hou Y, Shuai H, Yang D, Hu B, Huang X, Zhang X, Cai JP, Zhou J, Yuan S, Kok KH, To KK, Chan IH, Zhang AJ, Sit KY, Au WK, Yuen KY. Chu H, et al. Among authors: yuan s. Clin Infect Dis. 2020 Sep 12;71(6):1400-1409. doi: 10.1093/cid/ciaa410. Clin Infect Dis. 2020. PMID: 32270184 Free PMC article.
Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory studies of COVID-19: an observational study.
Chu H, Chan JF, Yuen TT, Shuai H, Yuan S, Wang Y, Hu B, Yip CC, Tsang JO, Huang X, Chai Y, Yang D, Hou Y, Chik KK, Zhang X, Fung AY, Tsoi HW, Cai JP, Chan WM, Ip JD, Chu AW, Zhou J, Lung DC, Kok KH, To KK, Tsang OT, Chan KH, Yuen KY. Chu H, et al. Among authors: yuan s. Lancet Microbe. 2020 May;1(1):e14-e23. doi: 10.1016/S2666-5247(20)30004-5. Epub 2020 Apr 21. Lancet Microbe. 2020. PMID: 32835326 Free PMC article.
Coronavirus Disease 2019 (COVID-19) Re-infection by a Phylogenetically Distinct Severe Acute Respiratory Syndrome Coronavirus 2 Strain Confirmed by Whole Genome Sequencing.
To KK, Hung IF, Ip JD, Chu AW, Chan WM, Tam AR, Fong CH, Yuan S, Tsoi HW, Ng AC, Lee LL, Wan P, Tso EY, To WK, Tsang DN, Chan KH, Huang JD, Kok KH, Cheng VC, Yuen KY. To KK, et al. Among authors: yuan s. Clin Infect Dis. 2021 Nov 2;73(9):e2946-e2951. doi: 10.1093/cid/ciaa1275. Clin Infect Dis. 2021. PMID: 32840608 Free PMC article.
Emerging SARS-CoV-2 variants expand species tropism to murines.
Shuai H, Chan JF, Yuen TT, Yoon C, Hu JC, Wen L, Hu B, Yang D, Wang Y, Hou Y, Huang X, Chai Y, Chan CC, Poon VK, Lu L, Zhang RQ, Chan WM, Ip JD, Chu AW, Hu YF, Cai JP, Chan KH, Zhou J, Sridhar S, Zhang BZ, Yuan S, Zhang AJ, Huang JD, To KK, Yuen KY, Chu H. Shuai H, et al. Among authors: yuan s. EBioMedicine. 2021 Nov;73:103643. doi: 10.1016/j.ebiom.2021.103643. Epub 2021 Oct 21. EBioMedicine. 2021. PMID: 34689086 Free PMC article.
Attenuated replication and pathogenicity of SARS-CoV-2 B.1.1.529 Omicron.
Shuai H, Chan JF, Hu B, Chai Y, Yuen TT, Yin F, Huang X, Yoon C, Hu JC, Liu H, Shi J, Liu Y, Zhu T, Zhang J, Hou Y, Wang Y, Lu L, Cai JP, Zhang AJ, Zhou J, Yuan S, Brindley MA, Zhang BZ, Huang JD, To KK, Yuen KY, Chu H. Shuai H, et al. Among authors: yuan s. Nature. 2022 Mar;603(7902):693-699. doi: 10.1038/s41586-022-04442-5. Epub 2022 Jan 21. Nature. 2022. PMID: 35062016
Pathogenicity, transmissibility, and fitness of SARS-CoV-2 Omicron in Syrian hamsters.
Yuan S, Ye ZW, Liang R, Tang K, Zhang AJ, Lu G, Ong CP, Man Poon VK, Chan CC, Mok BW, Qin Z, Xie Y, Chu AW, Chan WM, Ip JD, Sun H, Tsang JO, Yuen TT, Chik KK, Chan CC, Cai JP, Luo C, Lu L, Yip CC, Chu H, To KK, Chen H, Jin DY, Yuen KY, Chan JF. Yuan S, et al. Science. 2022 Jul 22;377(6604):428-433. doi: 10.1126/science.abn8939. Epub 2022 Jun 23. Science. 2022. PMID: 35737809 Free article.
Virological features and pathogenicity of SARS-CoV-2 Omicron BA.2.
Chan JF, Hu B, Chai Y, Shuai H, Liu H, Shi J, Liu Y, Yoon C, Zhang J, Hu JC, Hou Y, Huang X, Yuen TT, Zhu T, Li W, Cai JP, Luo C, Yip CC, Zhang AJ, Zhou J, Yuan S, Zhang BZ, Huang JD, To KK, Yuen KY, Chu H. Chan JF, et al. Among authors: yuan s. Cell Rep Med. 2022 Sep 20;3(9):100743. doi: 10.1016/j.xcrm.2022.100743. Epub 2022 Aug 29. Cell Rep Med. 2022. PMID: 36084644 Free PMC article.
Intranasal Boosting with Spike Fc-RBD of Wild-Type SARS-CoV-2 Induces Neutralizing Antibodies against Omicron Subvariants and Reduces Viral Load in the Nasal Turbinate of Mice.
Cai JP, Luo C, Wang K, Cao H, Chen LL, Zhang X, Han Y, Yin F, Zhang AJ, Chu H, Yuan S, Kok KH, To KK, Chen H, Chen Z, Jin DY, Yuen KY, Chan JF. Cai JP, et al. Among authors: yuan s. Viruses. 2023 Mar 6;15(3):687. doi: 10.3390/v15030687. Viruses. 2023. PMID: 36992395 Free PMC article.
7,982 results