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Multivariate data analysis of process parameters affecting the growth and productivity of stable Chinese hamster ovary cell pools expressing SARS-CoV-2 spike protein as vaccine antigen in early process development.
Reyes SJ, Lemire L, Molina RS, Roy M, L'Ecuyer-Coelho H, Martynova Y, Cass B, Voyer R, Durocher Y, Henry O, Pham PL. Reyes SJ, et al. Among authors: durocher y. Biotechnol Prog. 2024 Apr 25:e3467. doi: 10.1002/btpr.3467. Online ahead of print. Biotechnol Prog. 2024. PMID: 38660973
Influence of variant-specific mutations, temperature and pH on conformations of a large set of SARS-CoV-2 spike trimer vaccine antigen candidates.
Stuible M, Schrag JD, Sheff J, Zoubchenok D, Lord-Dufour S, Cass B, L'Abbé D, Pelletier A, Rossotti MA, Tanha J, Gervais C, Maurice R, El Bakkouri M, Acchione M, Durocher Y. Stuible M, et al. Among authors: durocher y. Sci Rep. 2023 Oct 1;13(1):16498. doi: 10.1038/s41598-023-43661-2. Sci Rep. 2023. PMID: 37779126 Free PMC article.
Tuning the immune response: sulfated archaeal glycolipid archaeosomes as an effective vaccine adjuvant for induction of humoral and cell-mediated immunity towards the SARS-CoV-2 Omicron variant of concern.
Renner TM, Akache B, Stuible M, Rohani N, Cepero-Donates Y, Deschatelets L, Dudani R, Harrison BA, Baardsnes J, Koyuturk I, Hill JJ, Hemraz UD, Régnier S, Lenferink AEG, Durocher Y, McCluskie MJ. Renner TM, et al. Among authors: durocher y. Front Immunol. 2023 Apr 14;14:1182556. doi: 10.3389/fimmu.2023.1182556. eCollection 2023. Front Immunol. 2023. PMID: 37122746 Free PMC article.
Intranasal administration of unadjuvanted SARS-CoV-2 spike antigen boosts antigen-specific immune responses induced by parenteral protein subunit vaccine prime in mice and hamsters.
Agbayani G, Akache B, Renner TM, Tran A, Stuible M, Dudani R, Harrison BA, Duque D, Bavananthasivam J, Deschatelets L, Hemraz UD, Régnier S, Durocher Y, McCluskie MJ. Agbayani G, et al. Among authors: durocher y. Eur J Immunol. 2024 Apr 1:e2350620. doi: 10.1002/eji.202350620. Online ahead of print. Eur J Immunol. 2024. PMID: 38561974
CHO cells for virus-like particle and subunit vaccine manufacturing.
Sanchez-Martinez ZV, Alpuche-Lazcano SP, Stuible M, Durocher Y. Sanchez-Martinez ZV, et al. Among authors: durocher y. Vaccine. 2024 Apr 11;42(10):2530-2542. doi: 10.1016/j.vaccine.2024.03.034. Epub 2024 Mar 19. Vaccine. 2024. PMID: 38503664 Free article. Review.
187 results