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Natural Killer cells demonstrate distinct eQTL and transcriptome-wide disease associations, highlighting their role in autoimmunity.
Gilchrist JJ, Makino S, Naranbhai V, Sharma PK, Koturan S, Tong O, Taylor CA, Watson RA, de Los Aires AV, Cooper R, Lau E, Danielli S, Hameiri-Bowen D, Lee W, Ng E, Whalley J, Knight JC, Fairfax BP. Gilchrist JJ, et al. Nat Commun. 2022 Jul 14;13(1):4073. doi: 10.1038/s41467-022-31626-4. Nat Commun. 2022. PMID: 35835762 Free PMC article.
IL7 genetic variation and toxicity to immune checkpoint blockade in patients with melanoma.
Taylor CA, Watson RA, Tong O, Ye W, Nassiri I, Gilchrist JJ, de Los Aires AV, Sharma PK, Koturan S, Cooper RA, Woodcock VK, Jungkurth E, Shine B, Coupe N, Payne MJ, Church DN, Naranbhai V, Groha S, Emery P, Mankia K, Freedman ML, Choueiri TK, Middleton MR, Gusev A, Fairfax BP. Taylor CA, et al. Among authors: gilchrist jj. Nat Med. 2022 Dec;28(12):2592-2600. doi: 10.1038/s41591-022-02095-5. Epub 2022 Dec 16. Nat Med. 2022. PMID: 36526722 Free PMC article.
A common NFKB1 variant detected through antibody analysis in UK Biobank predicts risk of infection and allergy.
Chong AY, Brenner N, Jimenez-Kaufmann A, Cortes A, Hill M, Littlejohns TJ, Gilchrist JJ, Fairfax BP, Knight JC, Hodel F, Fellay J, McVean G, Moreno-Estrada A, Waterboer T, Hill AVS, Mentzer AJ. Chong AY, et al. Among authors: gilchrist jj. Am J Hum Genet. 2024 Feb 1;111(2):295-308. doi: 10.1016/j.ajhg.2023.12.013. Epub 2024 Jan 16. Am J Hum Genet. 2024. PMID: 38232728 Free PMC article.
Risk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT4.
Gilchrist JJ, Rautanen A, Fairfax BP, Mills TC, Naranbhai V, Trochet H, Pirinen M, Muthumbi E, Mwarumba S, Njuguna P, Mturi N, Msefula CL, Gondwe EN, MacLennan JM, Chapman SJ, Molyneux ME, Knight JC, Spencer CCA, Williams TN, MacLennan CA, Scott JAG, Hill AVS. Gilchrist JJ, et al. Nat Commun. 2018 Mar 9;9(1):1014. doi: 10.1038/s41467-017-02398-z. Nat Commun. 2018. PMID: 29523850 Free PMC article.
Genome-wide association study of leprosy in Malawi and Mali.
Gilchrist JJ, Auckland K, Parks T, Mentzer AJ, Goldblatt L, Naranbhai V, Band G, Rockett KA, Toure OB, Konate S, Sissoko S, Djimdé AA, Thera MA, Doumbo OK, Sow S, Floyd S, Pönnighaus JM, Warndorff DK, Crampin AC, Fine PEM, Fairfax BP, Hill AVS. Gilchrist JJ, et al. PLoS Pathog. 2022 Sep 19;18(9):e1010312. doi: 10.1371/journal.ppat.1010312. eCollection 2022 Sep. PLoS Pathog. 2022. PMID: 36121873 Free PMC article.
BIRC6 modifies risk of invasive bacterial infection in Kenyan children.
Gilchrist JJ, Kariuki SN, Watson JA, Band G, Uyoga S, Ndila CM, Mturi N, Mwarumba S, Mohammed S, Mosobo M, Alasoo K, Rockett KA, Mentzer AJ, Kwiatkowski DP, Hill AVS, Maitland K, Scott JAG, Williams TN. Gilchrist JJ, et al. Elife. 2022 Jul 22;11:e77461. doi: 10.7554/eLife.77461. Elife. 2022. PMID: 35866869 Free PMC article.
Genetic variation in VAC14 is associated with bacteremia secondary to diverse pathogens in African children.
Gilchrist JJ, Mentzer AJ, Rautanen A, Pirinen M, Mwarumba S, Njuguna P, Mturi N; Wellcome Trust Case-Control Consortium 2; Kenyan Bacteraemia Study Group; Williams TN, Scott JAG, Hill AVS. Gilchrist JJ, et al. Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):E3601-E3603. doi: 10.1073/pnas.1802071115. Epub 2018 Mar 27. Proc Natl Acad Sci U S A. 2018. PMID: 29588414 Free PMC article. No abstract available.
29 results