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Stratification of obesity phenotypes to optimize future therapy (SOPHIA).
Tahrani AA, Panova-Noeva M, Schloot NC, Hennige AM, Soderberg J, Nadglowski J, Tarasenko L, Ahmad NN, Sleypen BS, Bravo R, Al-Najim W, le Roux CW. Tahrani AA, et al. Among authors: hennige am. Expert Rev Gastroenterol Hepatol. 2023 Jul-Dec;17(10):1031-1039. doi: 10.1080/17474124.2023.2264783. Epub 2023 Oct 24. Expert Rev Gastroenterol Hepatol. 2023. PMID: 37791820 Review.
Phase I studies of the safety, tolerability, pharmacokinetics and pharmacodynamics of the dual glucagon receptor/glucagon-like peptide-1 receptor agonist BI 456906.
Jungnik A, Arrubla Martinez J, Plum-Mörschel L, Kapitza C, Lamers D, Thamer C, Schölch C, Desch M, Hennige AM. Jungnik A, et al. Among authors: hennige am. Diabetes Obes Metab. 2023 Apr;25(4):1011-1023. doi: 10.1111/dom.14948. Epub 2023 Jan 30. Diabetes Obes Metab. 2023. PMID: 36527386 Clinical Trial.
A randomized Phase I study of the safety, tolerability, pharmacokinetics and pharmacodynamics of BI 456906, a dual glucagon receptor/glucagon-like peptide-1 receptor agonist, in healthy Japanese men with overweight/obesity.
Yazawa R, Ishida M, Balavarca Y, Hennige AM. Yazawa R, et al. Among authors: hennige am. Diabetes Obes Metab. 2023 Jul;25(7):1973-1984. doi: 10.1111/dom.15064. Epub 2023 Apr 27. Diabetes Obes Metab. 2023. PMID: 36974349 Clinical Trial.
Perspectives in weight control in diabetes - Survodutide.
Klein T, Augustin R, Hennige AM. Klein T, et al. Among authors: hennige am. Diabetes Res Clin Pract. 2024 Jan;207:110779. doi: 10.1016/j.diabres.2023.110779. Epub 2023 Jun 15. Diabetes Res Clin Pract. 2024. PMID: 37330144
Dose-response effects on HbA1c and bodyweight reduction of survodutide, a dual glucagon/GLP-1 receptor agonist, compared with placebo and open-label semaglutide in people with type 2 diabetes: a randomised clinical trial.
Blüher M, Rosenstock J, Hoefler J, Manuel R, Hennige AM. Blüher M, et al. Among authors: hennige am. Diabetologia. 2024 Mar;67(3):470-482. doi: 10.1007/s00125-023-06053-9. Epub 2023 Dec 14. Diabetologia. 2024. PMID: 38095657 Free PMC article. Clinical Trial.
Correction to: Dose-response effects on HbA1c and bodyweight reduction of survodutide, a dual glucagon/GLP-1 receptor agonist, compared with placebo and open-label semaglutide in people with type 2 diabetes: a randomised clinical trial.
Blüher M, Rosenstock J, Hoefler J, Manuel R, Hennige AM. Blüher M, et al. Among authors: hennige am. Diabetologia. 2024 Apr;67(4):758. doi: 10.1007/s00125-024-06095-7. Diabetologia. 2024. PMID: 38349400 Free PMC article. No abstract available.
Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits.
Brown AA, Fernandez-Tajes JJ, Hong MG, Brorsson CA, Koivula RW, Davtian D, Dupuis T, Sartori A, Michalettou TD, Forgie IM, Adam J, Allin KH, Caiazzo R, Cederberg H, De Masi F, Elders PJM, Giordano GN, Haid M, Hansen T, Hansen TH, Hattersley AT, Heggie AJ, Howald C, Jones AG, Kokkola T, Laakso M, Mahajan A, Mari A, McDonald TJ, McEvoy D, Mourby M, Musholt PB, Nilsson B, Pattou F, Penet D, Raverdy V, Ridderstråle M, Romano L, Rutters F, Sharma S, Teare H, 't Hart L, Tsirigos KD, Vangipurapu J, Vestergaard H, Brunak S, Franks PW, Frost G, Grallert H, Jablonka B, McCarthy MI, Pavo I, Pedersen O, Ruetten H, Walker M; DIRECT Consortium; Adamski J, Schwenk JM, Pearson ER, Dermitzakis ET, Viñuela A. Brown AA, et al. Nat Commun. 2023 Aug 21;14(1):5062. doi: 10.1038/s41467-023-40569-3. Nat Commun. 2023. PMID: 37604891 Free PMC article.
76 results