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Minimizing higher-order aggregation maximizes iron mobilization by small molecules.
Nat Chem Biol. 2024 Apr 25. doi: 10.1038/s41589-024-01596-3. Online ahead of print.
Nat Chem Biol. 2024.
PMID: 38664586
A small molecule redistributes iron in ferroportin-deficient mice and patient-derived primary macrophages.
Ekaputri S, Choi EK, Sabelli M, Aring L, Green KJ, Chang J, Bao K, Choi HS, Iwase S, Kim J, Corradini E, Pietrangelo A, Burke MD, Seo YA.
Ekaputri S, et al.
Proc Natl Acad Sci U S A. 2022 Jun 28;119(26):e2121400119. doi: 10.1073/pnas.2121400119. Epub 2022 Jun 22.
Proc Natl Acad Sci U S A. 2022.
PMID: 35737834
Free PMC article.
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